Document Detail


Domain general change detection accounts for "dishabituation" effects in temporal-parietal regions in functional magnetic resonance imaging studies of speech perception.
MedLine Citation:
PMID:  20089919     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Functional magnetic resonance imaging (fMRI) studies of speech sound categorization often compare conditions in which a stimulus is presented repeatedly to conditions in which multiple stimuli are presented. This approach has established that a set of superior temporal and inferior parietal regions respond more strongly to conditions containing stimulus change. Here, we examine whether this contrast is driven by habituation to a repeating condition or by selective responding to change. Experiment 1 directly tests this by comparing the observed response to long trains of stimuli against a constructed hemodynamic response modeling the hypothesis that no habituation occurs. The results are consistent with the view that enhanced response to conditions involving phonemic variability reflect change detection. In a second experiment, the specificity of these responses to linguistically relevant stimulus variability was studied by including a condition in which the talker, rather than phonemic category, was variable from stimulus to stimulus. In this context, strong change detection responses were observed to changes in talker, but not to changes in phoneme category. The results prompt a reconsideration of two assumptions common to fMRI studies of speech sound categorization: they suggest that temporoparietal responses in passive paradigms such as those used here are better characterized as reflecting change detection than habituation, and that their apparent selectivity to speech sound categories may reflect a more general preference for variability in highly salient or behaviorally relevant stimulus dimensions.
Authors:
Jason D Zevin; Jianfeng Yang; Jeremy I Skipper; Bruce D McCandliss
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The Journal of neuroscience : the official journal of the Society for Neuroscience     Volume:  30     ISSN:  1529-2401     ISO Abbreviation:  J. Neurosci.     Publication Date:  2010 Jan 
Date Detail:
Created Date:  2010-01-21     Completed Date:  2010-02-05     Revised Date:  2014-09-21    
Medline Journal Info:
Nlm Unique ID:  8102140     Medline TA:  J Neurosci     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1110-7     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Acoustic Stimulation / methods
Brain Mapping*
Female
Humans
Image Processing, Computer-Assisted / methods
Inhibition (Psychology)*
Magnetic Resonance Imaging*
Oxygen / blood
Parietal Lobe / blood supply*,  physiology
Phonetics
Psycholinguistics / methods
Speech Perception / physiology*
Statistics as Topic
Temporal Lobe / blood supply*,  physiology
Time Factors
Grant Support
ID/Acronym/Agency:
R01 DC007694/DC/NIDCD NIH HHS; R01 DC007694-03/DC/NIDCD NIH HHS; R01 DC007694-04/DC/NIDCD NIH HHS; R01 DC007694-05/DC/NIDCD NIH HHS; R01-DC007694/DC/NIDCD NIH HHS; R21 DC008969/DC/NIDCD NIH HHS; R21 DC008969-01A2/DC/NIDCD NIH HHS; R21-DC0008969/DC/NIDCD NIH HHS
Chemical
Reg. No./Substance:
S88TT14065/Oxygen
Comments/Corrections

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