Document Detail

Dolichoectasia Diagnostic Methods in a Multi-Ethnic, Stroke-Free Cohort: Results from the Northern Manhattan Study.
MedLine Citation:
PMID:  23317292     Owner:  NLM     Status:  Publisher    
BACKGROUND AND PURPOSE: Dolichoectasia (DE) is a vasculopathy that consists of abnormal elongation and dilatation of arteries. The objective of this study is to evaluate the frequency of DE in an unselected population and assess different diagnostic methods. METHODS: The Northern Manhattan Study is a multiethnic population based cohort of stroke-free participants. The definition proposed for DE was total cranial volume (TCV)-adjusted arterial diameter ≥2 SD. Other methods studied included visual assessment, unadjusted arterial diameters cutoff, Smoker's criteria and basilar artery (BA) volume. RESULTS: A total of 718 subjects were included in the analysis (mean age 71.6 ± 8.0 years, 40% men, 61% Hispanic). Using the TCV-adjusted DE definition, 19% of the sample had at least one dolichoectatic artery. In 7% of the subjects, two or more arteries were affected. The BA was the most common dolichoectatic artery. Reproducibility for arterial diameter measurements was good to excellent (.70-.95), while for visual assessment ranged from fair to good (.49-.79). CONCLUSIONS: A TCV-adjusted intracranial arterial diameter ≥2 SD is proposed as a useful DE definition. The variability in the prevalence of DE depending on the methods used underscores the need to agree on a reliable, universal definition of DE.
Jose Gutierrez; Ahmet Bagci; Hannah Gardener; Tatjana Rundek; Mitchell S V Ekind; Noam Alperin; Ralph L Sacco; Clinton B Wright
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-1-14
Journal Detail:
Title:  Journal of neuroimaging : official journal of the American Society of Neuroimaging     Volume:  -     ISSN:  1552-6569     ISO Abbreviation:  J Neuroimaging     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2013-1-15     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9102705     Medline TA:  J Neuroimaging     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2013 by the American Society of Neuroimaging.
From the Department of Neurology, College of Physicians and Surgeons, Columbia University, New York, NY (JG, MSVE); Department of Radiology, University of Miami, Miami, FL (AB, NA); Department of Neurology, Miller School of Medicine, University of Miami, Miami, FL (HG, TR, RLS, CBW); Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY (MSVE).
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