Document Detail

Does a vitrified blastocyst stage embryo transfer program need hormonal priming for endometrial preparation?
MedLine Citation:
PMID:  20666946     Owner:  NLM     Status:  MEDLINE    
AIM: To compare the clinical outcomes of a vitrified blastocyst stage embryo transfer (ET) program among natural, ovulation induced and artificial cycles.
MATERIAL & METHODS: The clinical outcomes were retrospectively analyzed in three groups according to endometrial preparation (natural cycle group [n = 34], ovulation induced [n = 21], and artificial cycles [n = 70]) among women that underwent vitrified blastocyst stage ET.
RESULTS: The overall pregnancy rate was 48.8%. There were no significant differences in the duration of endometrial preparation, endometrial thickness on the day of progesterone or human chorionic gonadotropin administration, implantation and clinical pregnancy rates among the three groups. Triple-line endometrial patterns were more frequently observed in the natural and ovulation induced groups than in the artificial cycle group (85.3% vs 64.3%, P = 0.021; 90.5% vs 64.3%, P = 0.016).
CONCLUSION: Our findings suggest that the types of endometrial preparation may have no significant effect on the clinical outcomes of vitrified blastocyst ET. Hormonal priming does not appear to be a prerequisite for endometrial preparation for vitrified blastocyst ET.
Yong Jin Kim; Young Sik Choi; Won Don Lee; Ki Chul Kim; Byung Chul Jee; Chang Suk Suh; Seok Hyun Kim; Shin Yong Moon
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The journal of obstetrics and gynaecology research     Volume:  36     ISSN:  1447-0756     ISO Abbreviation:  J. Obstet. Gynaecol. Res.     Publication Date:  2010 Aug 
Date Detail:
Created Date:  2010-07-29     Completed Date:  2010-11-04     Revised Date:  2012-01-19    
Medline Journal Info:
Nlm Unique ID:  9612761     Medline TA:  J Obstet Gynaecol Res     Country:  Australia    
Other Details:
Languages:  eng     Pagination:  783-8     Citation Subset:  IM    
Department of Obstetrics and Gynecology, College of Medicine, Medical Research Center, Seoul National University, Seoul, Korea.
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MeSH Terms
Embryo Transfer / methods*
Endometrium / drug effects*
Estradiol / pharmacology
Ovulation Induction / methods*
Progesterone / pharmacology
Statistics, Nonparametric
Treatment Outcome
Reg. No./Substance:
50-28-2/Estradiol; 57-83-0/Progesterone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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