Document Detail


Does use of coils in addition to amplatzer vascular plugs prevent recanalization?
MedLine Citation:
PMID:  20729458     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: Recanalization has been reported with the use of a type 1 Amplatzer vascular plug as the sole device to manage a pulmonary arteriovenous malformation (PAVM). We evaluated our experience with the use of at least one coil in addition to the vascular plug whenever possible in the treatment of patients with a PAVM. MATERIALS AND METHODS: Thirty patients had 39 feeder vessels in 37 PAVMs managed with 39 type 1 Amplatzer vascular plugs. Eleven PAVMs (30%) were complex, and 26 (70%) were simple; nine (24%) were solitary. CT examinations were scheduled for 6 months after treatment and every 3-5 years thereafter. Scans were evaluated for persistent sac perfusion, sac shrinkage, and/or complete resolution of the PAVM. RESULTS: Complete occlusion of all PAVMs was achieved. The mean number of coils used in addition to a type 1 Amplatzer vascular plug was 1.5 (range, 0-5 coils). Six patients did not participate in follow-up; 24 patients with 28 PAVMs managed with type 1 Amplatzer vascular plugs underwent follow-up imaging (mean, 13 months after treatment; range, 6-40 months). No PAVM exhibited recanalization at follow-up CT. Sac shrinkage or disappearance was found in all cases, and the plug had a characteristic CT appearance. Longer-term surveillance imaging was scheduled for all patients. CONCLUSION: Used in conjunction with coils, the type 1 Amplatzer vascular plug offers excellent occlusion of PAVMs. No recanalization was found in this study.
Authors:
Scott O Trerotola; Reed E Pyeritz
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  AJR. American journal of roentgenology     Volume:  195     ISSN:  1546-3141     ISO Abbreviation:  AJR Am J Roentgenol     Publication Date:  2010 Sep 
Date Detail:
Created Date:  2010-08-23     Completed Date:  2010-09-28     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7708173     Medline TA:  AJR Am J Roentgenol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  766-71     Citation Subset:  AIM; IM    
Affiliation:
Department of Radiology, Division of Vascular and Interventional Radiology, University of Pennsylvania Medical Center, 1 Silverstein, 3400 Spruce St., Philadelphia, PA 19104, USA. streroto@uphs.upenn.edu
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Aged
Arteriovenous Malformations / radiography,  therapy*
Embolization, Therapeutic / instrumentation*
Female
Humans
Male
Middle Aged
Pulmonary Artery / abnormalities,  radiography
Pulmonary Veins / abnormalities,  radiography
Recurrence / prevention & control
Retrospective Studies
Septal Occluder Device*
Telangiectasia, Hereditary Hemorrhagic / radiography,  therapy*
Tomography, X-Ray Computed
Treatment Outcome*
Comments/Corrections
Comment In:
AJR Am J Roentgenol. 2010 Oct;195(4):836   [PMID:  20858806 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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