Document Detail

Does umbilical cord care in preterm infants influence cord bacterial colonization or detachment?
MedLine Citation:
PMID:  14762447     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: The purpose of the present study was to compare alcohol versus natural drying for umbilical cord care in preterm infants and to examine its effects on bacterial colonization and cord detachment. STUDY DESIGN AND METHODS: Eligible infants <34 weeks gestation admitted to the NICU were randomized to receive either umbilical cleansing with 70% isopropyl alcohol at each diaper change or natural drying. Umbilical stump cultures were performed at 12 to 24 hours, 72 hours, 7 days, and 14 days of age. RESULTS: A total of 109 infants were enrolled; 102 completed the study. Analyses revealed that the median cord detachment time was significantly shorter in the natural drying group compared to the alcohol group (13.0 versus 16.0 days; p=0.003). There were no cases of local umbilical infection in either group. CONCLUSION: Based on the present study, it appears that natural drying is a safe and effective means of umbilical cord care in preterm infants.
Kelley Evens; Jeffrey George; Denise Angst; Lorene Schweig
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Publication Detail:
Type:  Clinical Trial; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of perinatology : official journal of the California Perinatal Association     Volume:  24     ISSN:  0743-8346     ISO Abbreviation:  J Perinatol     Publication Date:  2004 Feb 
Date Detail:
Created Date:  2004-02-11     Completed Date:  2004-06-14     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8501884     Medline TA:  J Perinatol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  100-4     Citation Subset:  IM    
Lutheran General Children's Hospital, Park Ridge, IL 60068, USA.
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MeSH Terms
2-Propanol / administration & dosage*
Administration, Topical
Anti-Infective Agents, Local / administration & dosage*
Infant, Newborn
Infant, Premature*
Prospective Studies
Umbilical Cord / drug effects,  microbiology*
Umbilicus* / microbiology
Wound Healing / drug effects
Wound Infection / prevention & control*
Reg. No./Substance:
0/Anti-Infective Agents, Local; 67-63-0/2-Propanol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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