Document Detail

Does transplacental spread of coccidioidomycosis occur? Report of a neonatal fatality and review of the literature.
MedLine Citation:
PMID:  7018452     Owner:  NLM     Status:  MEDLINE    
A neonatal death due to unsuspected coccidioidomycosis was studied. A critical review of the 12 neonatal fatalities and two survivals now reported strongly opposes the concept of transplacental spread. Associated with 35 maternal fatalities in the literature are 16 cases of placentitis and five neonatal deaths; none of the neonatal deaths, however, were associated with placentitis. Three of these five had predominantly intrathoracic disease, as did those neonates whose rapid deaths were unassociated with maternal coccidioidomycosis. Transpartum aspiration of infected decidua or postpartum inhalation is the probable initial pathogenic event in neonatal coccidioidomycosis.
R P Spark
Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Archives of pathology & laboratory medicine     Volume:  105     ISSN:  0003-9985     ISO Abbreviation:  Arch. Pathol. Lab. Med.     Publication Date:  1981 Jul 
Date Detail:
Created Date:  1981-08-10     Completed Date:  1981-08-10     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7607091     Medline TA:  Arch Pathol Lab Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  347-50     Citation Subset:  AIM; IM    
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MeSH Terms
Coccidioidomycosis / mortality,  transmission*
Infant Mortality*
Infant, Newborn
Maternal-Fetal Exchange*
Placenta / microbiology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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