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Does therapy-related AML have a poor prognosis, independent of the cytogenetic/molecular determinants?
MedLine Citation:
PMID:  22127315     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Do patients with therapy-related acute myeloid leukemia (t-AML) have a poor prognosis independent of other predictive variables such as cytogenetics or molecular determinants? Limited data exist to answer this question in part because t-AML is often considered together with AML following myelodysplastic syndromes (MDS) in the category of secondary AML. This discussion provides some insight, based primarily on two published retrospective reviews of the German cooperative groups, into the question of whether t-AML is an independent adverse variable.
Authors:
Eric J Feldman
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Publication Detail:
Type:  Journal Article     Date:  2011-11-02
Journal Detail:
Title:  Best practice & research. Clinical haematology     Volume:  24     ISSN:  1532-1924     ISO Abbreviation:  Best Pract Res Clin Haematol     Publication Date:  2011 Dec 
Date Detail:
Created Date:  2011-11-30     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101120659     Medline TA:  Best Pract Res Clin Haematol     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  523-6     Citation Subset:  IM    
Copyright Information:
Copyright © 2011 Elsevier Ltd. All rights reserved.
Affiliation:
Weill Cornell Medical College, 525 East 68th Street, NY 10021, USA.
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