| Does symptom-limited cycle exercise cause low frequency diaphragm fatigue in patients with heart failure? | |
| | |
MedLine Citation:
|
PMID: 16081318 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
BACKGROUND: Reduced diaphragm contractility occurs in some healthy subjects when they exercise to exhaustion. This indicates low frequency fatigue, which may contribute to task failure. We hypothesised that patients with congestive heart failure (CHF) might be especially vulnerable to the development of low frequency diaphragm fatigue after exhaustive exercise. AIMS: To study the effect of exhaustive incremental cycle exercise on diaphragm contractility in patients with CHF. METHODS: 12 patients with CHF with an ejection fraction of 36.5 +/- 7.3% and 12 healthy age-matched control subjects performed an incremental cycle test to exhaustion. The unpotentiated twitch transdiaphragmatic pressure (twitch Pdi) in response to bilateral anterolateral magnetic phrenic nerve stimulation (BAMPS) was measured before and after exercise. RESULTS: Twitch Pdi at baseline was 20.2 +/- 6.7 cm H2O in the CHF group and 20.3 +/- .3 cm H2O in the controls (p = 0.957). 25 and 35 min post exercise the values were 19.9+/-5.4 and 20.0+/-5.1 cm H2O in the CHF group and 20.6 +/- 4.3 and 21.2 +/- 3.4 cm H2O in the control group; neither change was significant (F(2,27) = 0.007, p = 0.993; F(2,33) = 0.144, p = 0.866, respectively). CONCLUSION: When patients with CHF cycle to exhaustion, low frequency fatigue of the diaphragm does not occur, and this is unlikely to be an important factor limiting exercise capacity of such patients. |
| | |
Authors:
|
Mark J Dayer; Nicholas S Hopkinson; Ewen T Ross; Sophie Jonville; Tarek Sharshar; Mark Kearney; John Moxham; Michael I Polkey |
Related Documents
:
|
16158008 - Exercise duration and peak systolic blood pressure are predictive of mortality in ambul... 18996048 - Dyspnoea versus fatigue: additional prognostic information from symptoms in chronic hea... 12397568 - The prognostic value of body mass index and standard exercise testing in male veterans ... 15860388 - Effects of short-term moderate exercise training on sexual function in male patients wi... 3898798 - Comparison of stress digital ventriculography, stress thallium scintigraphy, and digita... 1481938 - Metabolic and respiratory effects of infused sodium acetate in healthy human subjects. |
Publication Detail:
|
Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't Date: 2005-08-02 |
Journal Detail:
|
Title: European journal of heart failure Volume: 8 ISSN: 1388-9842 ISO Abbreviation: Eur. J. Heart Fail. Publication Date: 2006 Jan |
Date Detail:
|
Created Date: 2006-01-02 Completed Date: 2006-04-18 Revised Date: 2011-06-08 |
Medline Journal Info:
|
Nlm Unique ID: 100887595 Medline TA: Eur J Heart Fail Country: Netherlands |
Other Details:
|
Languages: eng Pagination: 68-73 Citation Subset: IM |
Affiliation:
|
Respiratory Muscle Laboratory, Royal Brompton and Harefield N.H.S Trust, Royal Brompton Hospital, London, UK. markdayer@gmail.com |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Diaphragm
/
physiopathology* Exercise Test / adverse effects* Forced Expiratory Volume / physiology Heart Failure / physiopathology* Humans Male Middle Aged Muscle Fatigue / physiology* Physical Exertion / physiology* Prognosis Retrospective Studies Severity of Illness Index |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: The 5-lipoxygenase pathway in arterial wall biology and atherosclerosis.
Next Document: The impact of morbid events on survival following hospitalization for complicated myocardial infarct...