| Does subtle progesterone rise on the day of HCG affect pregnancy rate in long agonist ICSI cycles? | |
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MedLine Citation:
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PMID: 19459040 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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PURPOSE: To evaluate the impact of subtle progesterone (P4) rise on the day of HCG on pregnancy outcome in ICSI patients stimulated with long agonist protocol. METHODS: One hundred forty-nine consecutive controlled ovarian hyperstimulation cycles for ICSI using long luteal agonist protocol. RESULTS: Mean serum progesterone on day of hCG was 0.88+/-0.51 ng/mL values > or =1 ng/mL were found in 34.2% of cycles. Serum E2 on day of hCG and number of oocytes retrieved were significantly higher in the group with P4 > or = 1 ng/mL. The area under ROC for serum progesterone in prediction of pregnancy was 0.52, indicating that within the values studied, serum progesterone on day of hCG is not predictive of pregnancy outcome. CONCLUSION: P4 values > or =1 ng/mL on day of hCG are common in long agonist ICSI cycles particularly with high response. Within the P4 values encountered in this study, implantation and pregnancy rates are not adversely affected. |
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Authors:
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Hisham Ali Saleh; Mervat Sheikh El-Arab Omran; Mohamed Draz |
Publication Detail:
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Type: Journal Article Date: 2009-05-21 |
Journal Detail:
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Title: Journal of assisted reproduction and genetics Volume: 26 ISSN: 1573-7330 ISO Abbreviation: J. Assist. Reprod. Genet. Publication Date: 2009 May |
Date Detail:
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Created Date: 2009-07-31 Completed Date: 2009-11-16 Revised Date: 2010-09-27 |
Medline Journal Info:
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Nlm Unique ID: 9206495 Medline TA: J Assist Reprod Genet Country: Netherlands |
Other Details:
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Languages: eng Pagination: 239-42 Citation Subset: IM |
Affiliation:
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Department of Obstetrics and Gynecology, Alexandria University, Alexandria, Egypt. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Chorionic Gonadotropin / blood* Embryo Transfer Estradiol / blood Female Follicle Stimulating Hormone / blood Humans Luteal Phase Male Ovarian Follicle / pathology Ovary / pathology Pregnancy Pregnancy Rate Progesterone / blood* Sperm Injections, Intracytoplasmic / methods* |
| Chemical | |
Reg. No./Substance:
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0/Chorionic Gonadotropin; 50-28-2/Estradiol; 57-83-0/Progesterone; 9002-68-0/Follicle Stimulating Hormone |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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