Document Detail

Does raised intraocular pressure begin in utero?
MedLine Citation:
PMID:  9924297     Owner:  NLM     Status:  MEDLINE    
AIM: To determine whether fetal and infant growth, as assessed by weight at birth and weight at 1 year, are related to intraocular pressure. METHODS: 717 men and women born in Hertfordshire between 1920 and 1930, for whom records of birth weight and weight at 1 year were available, were examined. Visual fields were assessed using the Takagi central 25 degrees 75 point static threshold screening program. Tonometry was performed using the Perkin's tonometer. The disc was assessed by direct ophthalmoscopy through dilated pupils. RESULTS: A significant inverse relation was found between systolic blood pressure and birth weight. However, no association was found between birth weight or weight at 1 year and intraocular pressure, cup/disc ratio, or visual field defects. CONCLUSIONS: There was no evidence to support fetal or infant growth as being important factors for the subsequent development of raised intraocular pressure.
A J Foss; A Rauf; A Aihie Sayer; J R Evans; C Cooper; R P Wormald; D J Barker
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The British journal of ophthalmology     Volume:  82     ISSN:  0007-1161     ISO Abbreviation:  Br J Ophthalmol     Publication Date:  1998 Oct 
Date Detail:
Created Date:  1999-02-08     Completed Date:  1999-02-08     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0421041     Medline TA:  Br J Ophthalmol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  1125-30     Citation Subset:  IM    
Queen's Medical Centre, University Hospital, Nottingham.
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MeSH Terms
Birth Weight / physiology
Blood Pressure / physiology
Body Weight / physiology*
Embryonic and Fetal Development / physiology*
Glaucoma, Open-Angle / embryology*
Growth / physiology*
Infant, Newborn
Intraocular Pressure / physiology*
Middle Aged
Optic Disk
Tonometry, Ocular / methods
Visual Fields / physiology
Grant Support
//Wellcome Trust

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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