| Does radiographic emphysema correlate with low bone mineral density? | |
| | |
MedLine Citation:
|
PMID: 22273685 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
|
PURPOSE OF REVIEW: Several large epidemiologic studies have shown an association between chronic obstructive pulmonary disease (COPD) and osteoporosis. Recent studies have further implied an emphysema-specific association with low bone mineral density independent of obstruction severity. RECENT FINDINGS: This review will outline the studies demonstrating an independent association between radiographic emphysema and decreased bone mineral density and will discuss potential disease mechanisms, including systemic inflammation and immune-mediated factors, linking these disease processes. SUMMARY: Radiographic emphysema should be considered an independent risk factor in studies examining the mechanisms underlying COPD-related bone loss. Future research focused on the relationship between emphysema and low bone mineral density could provide mechanistic insight and result in the development of targeted therapies designed to halt progression of both disease processes. |
| | |
Authors:
|
Jessica Bon |
Related Documents
:
|
10150105 - Tumor endoprostheses vs. bone grafts in bone tumor surgery: experiences in hungary. 22386105 - The mechanical behavior of pmma/bone specimens extracted from augmented vertebrae: a nu... 14763695 - Living cells in 1 of 2 frozen femoral heads. 16161735 - Maxillary sinus augmentation: histologic and histomorphometric analysis. 6989255 - Combined z-plasty and horizontal shortening procedure for ectropion. 19487135 - Aspiration alone versus aspiration and bupivacaine injection in the treatment of undisp... |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Current opinion in pulmonary medicine Volume: 18 ISSN: 1531-6971 ISO Abbreviation: Curr Opin Pulm Med Publication Date: 2012 Mar |
Date Detail:
|
Created Date: 2012-01-25 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 9503765 Medline TA: Curr Opin Pulm Med Country: United States |
Other Details:
|
Languages: eng Pagination: 125-30 Citation Subset: IM |
Affiliation:
|
Division of Pulmonary Allergy and Critical Care Medicine, Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Implication of cysteine residues in the selection of oxorhenium inhibitors of cyclophilin hCyp18.
Next Document: Secondhand tobacco smoke: an occupational hazard for smoking and non-smoking bar and nightclub emplo...