Document Detail


Does pulmonary valve replacement post repair of tetralogy of Fallot improve right ventricular function?
MedLine Citation:
PMID:  19567499     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A best evidence topic in cardiac surgery was written according to a structured protocol. The question addressed was whether pulmonary valve replacement (PVR) after repair of tetralogy of Fallot improved outcomes including right ventricular (RV) function. Altogether 730 relevant papers were identified using the below mentioned search, 19 papers represented the best evidence to answer the question. The author, journal, date and country of publication, patient group studied, study type, relevant outcomes, results and study weaknesses were tabulated. We conclude that PVR after tetralogy of Fallot repair has been shown to improve RV function and to offer symptomatic benefit. Several retrospective reviews report consistent reductions in RV end diastolic and systolic volumes and improvement in RV stroke volume, with one study also finding improvement in left ventricular stroke volume. PVR in this population appears to result in improved clinical outcome and can be performed with low mortality.
Authors:
Louise Adamson; Hunaid A Vohra; Marcus P Haw
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Publication Detail:
Type:  Journal Article; Review     Date:  2009-06-30
Journal Detail:
Title:  Interactive cardiovascular and thoracic surgery     Volume:  9     ISSN:  1569-9285     ISO Abbreviation:  Interact Cardiovasc Thorac Surg     Publication Date:  2009 Sep 
Date Detail:
Created Date:  2009-08-18     Completed Date:  2009-10-26     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101158399     Medline TA:  Interact Cardiovasc Thorac Surg     Country:  England    
Other Details:
Languages:  eng     Pagination:  520-7     Citation Subset:  IM    
Affiliation:
Department of Cardiothoracic Surgery, Southampton General Hospital, Southampton, UK.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Aged
Benchmarking
Cardiac Surgical Procedures*
Child
Evidence-Based Medicine
Female
Heart Valve Prosthesis Implantation*
Humans
Male
Middle Aged
Pulmonary Valve / surgery*
Stroke Volume
Tetralogy of Fallot / physiopathology,  surgery*
Treatment Outcome
Ventricular Dysfunction, Left
Ventricular Function, Right*
Young Adult

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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