| Does prior infertility increase the risk of tubal pregnancy? | |
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MedLine Citation:
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PMID: 3595915 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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One hundred forty-nine patients who underwent surgery for tubal pregnancy at five hospitals in Seattle (WA) between 1975 and 1979 were interviewed to determine the risk factors for this disorder. Their responses were compared with those of 706 control women who had conceived an intrauterine pregnancy during the same time period during which the tubal pregnancies occurred. A higher proportion of cases reported a history of infertility (attempt to conceive without success for a period of at least 1 year) than controls (relative risk [RR] = 2.5; 95% confidence interval [CI] = 1.7-3.7). Women who were diagnosed in the investigation of their infertility as having tubal or ovulatory dysfunction had relative risks of tubal pregnancy of 5.8 (95% CI = 2.1-16.4) and 3.4 (95% CI = 1.3-8.5), respectively. The average time over which subjects had attempted to conceive before index pregnancies that were planned was longer among cases (15.4 months) than among controls (6.9 months). These results support the hypothesis that a history of infertility predisposes women to an increased risk of tubal pregnancy. The authors also found that, among infertile women, about twice as many cases (14.3%) as controls (6.8%) were current fertility drug users (RR = 3.1; 95% CI = 1.1-9.1), which suggests that the use of fertility drug(s) may further increase the risk of tubal pregnancy. |
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Authors:
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C P Yang; W H Chow; J R Daling; N S Weiss; D E Moore |
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Publication Detail:
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Type: Journal Article; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: Fertility and sterility Volume: 48 ISSN: 0015-0282 ISO Abbreviation: Fertil. Steril. Publication Date: 1987 Jul |
Date Detail:
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Created Date: 1987-08-07 Completed Date: 1987-08-07 Revised Date: 2007-11-14 |
Medline Journal Info:
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Nlm Unique ID: 0372772 Medline TA: Fertil Steril Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 62-6 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Female Fertility Agents, Female / toxicity Humans Infertility, Female / complications* Pregnancy Pregnancy, Tubal / etiology* Risk Time Factors |
| Grant Support | |
ID/Acronym/Agency:
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1 N01 HD 02821/HD/NICHD NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/Fertility Agents, Female |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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