Document Detail

Does preeclamptic pregnancy increase fetal-maternal hemorrhage?
MedLine Citation:
PMID:  7541998     Owner:  NLM     Status:  MEDLINE    
Since pathologic changes of the placenta have been found in preeclamptic pregnancies, a relationship between fetal-maternal hemorrhage and preeclampsia was investigated. Sixty-two women with singleton pregnancies in the third trimester were studied. Thirty-one of these women with preeclampsia were matched with 31 normotensive healthy pregnant women. Maternal serum levels of alpha-fetoprotein (MSAFP) and Kleihauer-Betke (KB) test were determined to reflect the degree of fetal-maternal hemorrhage. There were no significant differences in MSAFP levels, MSAFP to creatinine ratio, or the appearance of fetal cells as measured by the KB test between preeclamptic pregnancies and matched controls. Our data do not suggest that fetal-maternal hemorrhage is increased in pregnant women with preeclampsia.
C D Hsu; K Smith; S F Hong; T R Johnson; Y Gollin; D W Chan
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  American journal of perinatology     Volume:  12     ISSN:  0735-1631     ISO Abbreviation:  Am J Perinatol     Publication Date:  1995 May 
Date Detail:
Created Date:  1995-08-24     Completed Date:  1995-08-24     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8405212     Medline TA:  Am J Perinatol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  205-7     Citation Subset:  IM    
Department of Gynecology and Obstetrics, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
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MeSH Terms
Case-Control Studies
Fetomaternal Transfusion / diagnosis,  epidemiology,  etiology*
Pre-Eclampsia / complications*,  epidemiology
alpha-Fetoproteins / analysis
Reg. No./Substance:

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