Document Detail

Does postoperative ventilation have an effect on the integrity of the anastomosis in repaired oesophageal atresia?
MedLine Citation:
PMID:  10365344     Owner:  NLM     Status:  MEDLINE    
Several authors have claimed that the use of postoperative ventilation or graded withdrawal of respiratory support reduces the incidence of anastomotic complications after repair of oesophageal atresia, particularly where the gap between the oesophageal ends has been extensive or where the anastomosis has been constructed under tension. Careful review of their data reveals little objective evidence to either support or refute this contention. Many institutions are achieving low leakage rates following oesophageal anastomosis in oesophageal atresia, but to date there has been no controlled study to show that the use of neck flexion, muscle paralysis, intubation and assisted ventilation postoperatively influences the integrity of the anastomosis. The sequence of observations that led to the presumed relationship between postoperative ventilation and oesophageal leak is reviewed. It would appear that the effect of postoperative ventilation and paralysis on the oesophageal anastomosis is yet to be determined.
S W Beasley
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Journal of paediatrics and child health     Volume:  35     ISSN:  1034-4810     ISO Abbreviation:  J Paediatr Child Health     Publication Date:  1999 Apr 
Date Detail:
Created Date:  1999-07-28     Completed Date:  1999-07-28     Revised Date:  2007-09-24    
Medline Journal Info:
Nlm Unique ID:  9005421     Medline TA:  J Paediatr Child Health     Country:  AUSTRALIA    
Other Details:
Languages:  eng     Pagination:  120-2     Citation Subset:  IM    
Department of Paediatric Surgery, Christchurch Hospital, New Zealand.
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MeSH Terms
Anastomosis, Surgical
Esophageal Atresia / surgery*
Esophagus / surgery*
Infant, Newborn
Intubation, Intratracheal / adverse effects*
Postoperative Care
Postoperative Complications / etiology
Respiration, Artificial / adverse effects*,  methods
Risk Assessment
Time Factors
Wound Healing / physiology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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