Document Detail

Does positive pressure ventilation increase arginine vasopressin in preterm neonates?
MedLine Citation:
PMID:  9536839     Owner:  NLM     Status:  MEDLINE    
AIM: To examine the effect of intermittent positive pressure ventilation (IPPV) on plasma arginine vasopressin concentration (pAVP) in preterm neonates. METHODS: Thirty five neonates were classified, at the time of blood sampling, into three groups: unstable ventilated; stable ventilated; and stable non-ventilated. A modification of an extraction method for pAVP was developed for use in studies on very small babies, and sampling methods were compared. RESULTS: The pAVP (median, range) was similar in the ventilated (1.85 pmol/l, 0.5 to 3.4) and non-ventilated (2.0, 0.5 to 2.6) stable babies, but was significantly higher (5.7, 1.1 to 25) in the unstable group. There was an inverse correlation between systolic blood pressure and pAVP concentration. CONCLUSIONS: This study shows that in preterm neonates pAVP concentration is affected by the clinical condition and blood pressure, but not by treatment with IPPV.
H J Lambert; P H Baylis; J A McAulay; M C Coulthard
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Archives of disease in childhood. Fetal and neonatal edition     Volume:  78     ISSN:  1359-2998     ISO Abbreviation:  Arch. Dis. Child. Fetal Neonatal Ed.     Publication Date:  1998 Jan 
Date Detail:
Created Date:  1998-04-16     Completed Date:  1998-04-16     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  9501297     Medline TA:  Arch Dis Child Fetal Neonatal Ed     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  F38-42     Citation Subset:  AIM; IM    
Department of Child Health, University of Newcastle upon Tyne.
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MeSH Terms
Arginine Vasopressin / blood*,  isolation & purification
Blood Pressure
Blood Specimen Collection / methods
Infant, Newborn
Infant, Premature / blood*,  physiology,  urine
Intermittent Positive-Pressure Ventilation*
Osmolar Concentration
Reg. No./Substance:
113-79-1/Arginine Vasopressin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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