Document Detail

Does physical exercise modify antioxidant requirements?
MedLine Citation:
PMID:  19079851     Owner:  NLM     Status:  MEDLINE    
Physical training is known to induce a biochemical adaptive response which might require an increase in the ingestion and/or the absorption of micronutrients. A question that is still being raised is whether acute or chronic exercise modifies antioxidant requirements. First, the present review brings to light the most crucial studies on the topic. Second, it interprets the established relationships between antioxidant micronutrient intakes and the adaptive response of antioxidant systems. Finally, it exposes the major questions connected with antioxidant micronutrient requirements for athletes. To this effect, the training-load interaction with nutrition is taken into account. As oxidative stress cannot be avoided, the imbalance between oxidants and antioxidants can be alleviated to minimise oxidative damage and outcomes. There is growing evidence that one specific antioxidant cannot by itself prevent oxidative stress-induced damage, as direct adverse effects of supplementation are attributed to undesirable synergic effects. Other effects can be supposed that limit the endogenous adaptive effect of training. High doses of antioxidant supplements can minimise the effects of radical oxygen species themselves or generate pro-oxidant effects. Effects are only exhibited when nutritional status is deficient. There are no convincing effects of supplementation in well-trained athletes. Risk/benefit analysis emerges on evidence for an unknown risk of supranutritional intakes, a supposed impairment of adaptive effects and a still unknown long-term risk. Appropriate status can be achieved by a diversified and balanced diet, adapted to specific needs, by awareness of high-density food intakes (avoiding products containing a low density of micronutrients).
I Margaritis; A S Rousseau
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Nutrition research reviews     Volume:  21     ISSN:  1475-2700     ISO Abbreviation:  Nutr Res Rev     Publication Date:  2008 Jun 
Date Detail:
Created Date:  2008-12-16     Completed Date:  2009-03-06     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9113797     Medline TA:  Nutr Res Rev     Country:  England    
Other Details:
Languages:  eng     Pagination:  3-12     Citation Subset:  IM    
French Food Safety Agency, Department for Evaluation of Nutritional and Health Risk, Maisons-Alfort, France.
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MeSH Terms
Adaptation, Physiological*
Antioxidants / administration & dosage*,  physiology
Dietary Supplements / adverse effects
Dose-Response Relationship, Drug
Exercise / physiology*
Micronutrients / administration & dosage,  physiology
Nutritional Physiological Phenomena / physiology*
Nutritional Requirements*
Nutritive Value
Oxidative Stress
Risk Assessment
Reg. No./Substance:
0/Antioxidants; 0/Micronutrients

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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