Document Detail

Does peritoneal dialysis affect halitosis in patients with end-stage renal disease?
MedLine Citation:
PMID:  20338971     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: There are various causes of halitosis, one of which is chronic renal failure. The objective of this study was to investigate halitosis levels in end-stage renal disease (ESRD) patients before and after peritoneal dialysis (PD) therapy.
METHODS: 42 subjects with ESRD were included in this study. The presence of halitosis was assessed using an organoleptic measurement and compared with blood urea nitrogen (BUN) levels and salivary flow rates. Decayed, missing, and filled teeth (DMFT) index and Community Periodontal Index (CPI) were calculated. All measurements were done before and after patients had received 3 months of PD therapy.
RESULTS: Mean serum BUN level was found to be lower (46.05 ± 13.30 vs 91.24 ± 31.28 mg/dL), salivary flow rate higher (0.34 ± 0.07 vs 0.26 ± 0.04 mL/minute), and halitosis level lower (2.39 ± 0.60 vs 3.90 ± 0.37) at the end of 3 months of PD therapy than at the beginning of PD therapy. There was no significant difference in CPI or DMFT index before and after PD therapy (p > 0.05). There was statistically significant positive correlation between the presence of halitosis and BUN levels (r = 0.702, p = 0.001 before PD; r = 0.45, p = 0.002 after PD) and a negative correlation between the presence of halitosis and salivary flow rates (r = -0.69, p = 0.000 before PD; r = -0.37, p = 0.01 after PD).
CONCLUSION: High BUN levels and low salivary flow rates were found to be associated with halitosis. PD may play an important role in decreasing the level of halitosis in ESRD patients.
Mustafa Keles; Ummuhan Tozoglu; Abdullah Uyanik; Abubekir Eltas; Yusuf Ziya Bayindir; Ramazan Cetinkaya; Osman Murat Bilge
Publication Detail:
Type:  Comparative Study; Journal Article     Date:  2010-03-25
Journal Detail:
Title:  Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis     Volume:  31     ISSN:  1718-4304     ISO Abbreviation:  Perit Dial Int     Publication Date:    2011 Mar-Apr
Date Detail:
Created Date:  2011-03-23     Completed Date:  2012-01-03     Revised Date:  2012-08-08    
Medline Journal Info:
Nlm Unique ID:  8904033     Medline TA:  Perit Dial Int     Country:  Canada    
Other Details:
Languages:  eng     Pagination:  168-72     Citation Subset:  IM    
Department of Nephrology, Faculty of Medicine, Atatürk University, Erzurum, Turkey.
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MeSH Terms
Blood Urea Nitrogen
Disease Progression
Follow-Up Studies
Halitosis / diagnosis,  etiology*,  metabolism
Kidney Failure, Chronic / complications*,  metabolism,  therapy
Middle Aged
Peritoneal Dialysis
Risk Factors
Saliva / secretion*
Young Adult

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