Document Detail


Does oral calcium supplementation lower high blood pressure? A double blind study.
MedLine Citation:
PMID:  3295037     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Eighteen unselected patients with untreated mild to moderate essential hypertension, whose average supine blood pressure after 2 months' observation on no treatment was 154/103 mmHg, were entered into a double-blind randomized crossover study of 1 month's treatment with calcium lactate gluconate (40 mmol of elemental calcium/day) and treatment with placebo for a further month. Despite a significant increase in total plasma calcium (P less than 0.01) and in 24-h urinary excretion of calcium (P less than 0.025) while taking calcium lactate gluconate, there was no fall in blood pressure with calcium supplementation compared to treatment with placebo.
Authors:
F P Cappuccio; N D Markandu; D R Singer; S J Smith; A C Shore; G A MacGregor
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Publication Detail:
Type:  Clinical Trial; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of hypertension     Volume:  5     ISSN:  0263-6352     ISO Abbreviation:  J. Hypertens.     Publication Date:  1987 Feb 
Date Detail:
Created Date:  1987-06-26     Completed Date:  1987-06-26     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  8306882     Medline TA:  J Hypertens     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  67-71     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Blood Pressure / drug effects*
Calcium / blood,  therapeutic use*
Clinical Trials as Topic
Double-Blind Method
Female
Humans
Hypertension / blood,  drug therapy*,  physiopathology
Male
Middle Aged
Random Allocation
Chemical
Reg. No./Substance:
7440-70-2/Calcium

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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