Document Detail


Does neuraxial anesthesia reduce intraoperative blood loss? A meta-analysis.
MedLine Citation:
PMID:  16980159     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
STUDY OBJECTIVE: To perform a meta-analysis of available randomized controlled trials to determine if neuraxial anesthesia would decrease blood loss, compared with general anesthesia. DESIGN: Retrospective analysis. SETTING: University medical center. MEASUREMENTS: The National Library of Medicine's PubMed database was searched from the period of 1966 to December 10, 2003 for all abstracts containing words related to neuraxial anesthesia and general anesthesia. The search was limited to randomized controlled trials and the English language and yielded 667 articles. MAIN RESULTS: A total of 66 articles met inclusion criteria and were used for the analysis. Overall, the use of spinal anesthesia resulted in significantly less estimated blood loss (EBL) (P < 0.0001), compared with epidural anesthesia (EA), which, in turn, resulted in significantly less EBL compared with general anesthesia (GA) or combined GA-EA (P < 0.0001). No significant difference between GA and GA-EA was noted when analysis was limited to studies directly comparing GA-EA and GA. CONCLUSIONS: Use of spinal anesthesia or EA is associated with a significant decrease in EBL when compared with that for GA or combined GA-EA.
Authors:
Jeffrey M Richman; Andrew J Rowlingson; David N Maine; Genevieve E Courpas; James F Weller; Christopher L Wu
Related Documents :
20349349 - Identification and differentiation of dragon's blood in works of art using gas chromato...
22035639 - Pulsatile extracorporeal circulation during on-pump cardiac surgery enhances aortic wal...
6851459 - The influence of cardiovascular function on gas exchange.
8987039 - Use of the laryngeal mask for closed circuit anesthesia.
21273409 - Vascularization of cytochrome oxidase-rich blobs in the primary visual cortex of squirr...
1207039 - Halothane anaesthesia of normal and dystrophic hamsters.
20707619 - Incorporating a parenchymal thermal diffusion cerebral blood flow probe in bedside asse...
3278659 - Oxygen enrichment of bag-valve-mask units during positive-pressure ventilation: a compa...
8781999 - Diagnostic paracentesis. a two-step approach.
Publication Detail:
Type:  Comparative Study; Journal Article; Meta-Analysis    
Journal Detail:
Title:  Journal of clinical anesthesia     Volume:  18     ISSN:  0952-8180     ISO Abbreviation:  J Clin Anesth     Publication Date:  2006 Sep 
Date Detail:
Created Date:  2006-09-18     Completed Date:  2006-10-26     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8812166     Medline TA:  J Clin Anesth     Country:  United States    
Other Details:
Languages:  eng     Pagination:  427-35     Citation Subset:  IM    
Affiliation:
Department of Anesthesiology and Critical Care Medicine, The Johns Hopkins University, Baltimore, MD 21287, USA. jrichma1@jhmi.edu
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Anesthesia, Epidural*
Anesthesia, General
Anesthesia, Spinal*
Blood Loss, Surgical / prevention & control*
Female
Humans
Male
Retrospective Studies

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Dexmedetomidine infusion is associated with enhanced renal function after thoracic surgery.
Next Document:  Transcutaneous monitoring of partial pressure of carbon dioxide in the elderly patient: a prospectiv...