| Does the nephrotic syndrome increase the risk of cardiovascular disease? | |
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MedLine Citation:
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PMID: 90759 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Cardiovascular mortality and morbidity were assessed, after a mean follow-up period of 5 years, in an unselected series of 159 adults presenting with the nephrotic syndrome between 1972 and 1975. 60% of the deaths were attributed to terminal renal failure, and the incidence of deaths from ischaemic heart-disease (IHD) was not significantly above normal. The proportion of patients experiencing angina and intermittent claudication and the prevalence of ischaemic electrocardiographic changes did not differ significantly from those of a London control population. At follow-up, hypertension was significantly more common (p less than 0.001) in male nephrotic patients than in controls. Earlier reports of a greatly increased incidence of IHD in unselected patients with the nephrotic syndrome were not confirmed. Routine treatment of hyperlipidaemia in the nephrotic syndrome is not, therefore, recommended. |
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Authors:
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V J Wass; R J Jarrett; C Chilvers; J S Cameron |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: Lancet Volume: 2 ISSN: 0140-6736 ISO Abbreviation: Lancet Publication Date: 1979 Sep |
Date Detail:
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Created Date: 1979-12-20 Completed Date: 1979-12-20 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 2985213R Medline TA: Lancet Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 664-7 Citation Subset: AIM; IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Aged Coronary Disease / epidemiology*, mortality Female Follow-Up Studies Humans Hypertension / epidemiology* London Male Middle Aged Nephrotic Syndrome / complications* Population Surveillance Questionnaires Risk Sex Ratio Time Factors |
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