Document Detail

Does necrotizing enterocolitis affect growth and neurodevelopmental outcome in very low birth weight infants?
MedLine Citation:
PMID:  22274546     Owner:  NLM     Status:  Publisher    
AIM: To evaluate the effect of necrotizing enterocolitis (NEC) on growth and neurodevelopmental outcome. PATIENTS AND METHODS: Neurodevelopmental outcome of 20 of 39 surviving very low birthweight infants (VLBW) diagnosed with NEC between 2007 and 2009 was compared with 40 control infants matched for gestational age and year of admission. Follow-up studies were performed at 18 and 24 months of corrected age. Bayley Scales of Infant Development-Second Edition scale was used for neurodevelopmental assessment. RESULTS: At 18-24 months corrected age, body weight, body length, and head circumference did not differ significantly between the NEC and without NEC groups. The median mental developmental index (62 vs. 75, p = 0.008) and psychomotor developmental index points (72 vs. 91.5, p = 0.002) were lower in infants with NEC compared to without NEC, respectively. Although the rate of neurodevelopmental impairment was slightly higher in infants with NEC, there were no differences between the groups according to the frequency of minimal impairment and cerebral palsy. Growth or neurodevelopmental outcome did not differ between the NEC survivors with and without surgery. CONCLUSION: Necrotizing enterocolitis has affected neurodevelopmental outcome but not growth in VLBW infants at 18-24 months of corrected age. Both those treated medically or requiring surgery need close neurodevelopmental follow-up for the first years of life.
Dilek Dilli; Zeynep Eras; Hülya Ozkan Ulu; Uğur Dilmen; Evrim Durgut Şakrucu
Related Documents :
16479086 - Congenital atrophoderma of pasini and pierini.
22802466 - Late onset group b streptococcal disease manifests as submandibular cellulitis.
16726446 - Hourly distribution of time of parturition in the domestic goat.
22322126 - Topical application of chlorhexidine to neonatal umbilical cords for prevention of omph...
16866766 - Season of birth, age and negative symptoms in a xhosa schizophrenia sample from the sou...
6355316 - Selective intrapartum chemoprophylaxis of neonatal group b streptococcal early-onset di...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-1-25
Journal Detail:
Title:  Pediatric surgery international     Volume:  -     ISSN:  1437-9813     ISO Abbreviation:  -     Publication Date:  2012 Jan 
Date Detail:
Created Date:  2012-1-25     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8609169     Medline TA:  Pediatr Surg Int     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Department of Neonatology, Zekai Tahir Burak Maternity and Teaching Hospital, Ankara, Turkey,
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  A history of early stent thrombosis is associated with prolonged clot lysis time.
Next Document:  Therapeutic outcome and prognosis in young patients with papillary and follicular thyroid cancer.