Document Detail

Does mild valvular aortic stenosis progress during childhood?
MedLine Citation:
PMID:  16480005     Owner:  NLM     Status:  MEDLINE    
BACKGROUND AND AIM OF THE STUDY: An increased gradient in congenital valvular aortic stenosis (AS) during follow up remains the subject of controversy, and may determine a need for treatment in pediatric patients. It is hypothesized that a valvular gradient < 40 mmHg indicates a stable tendency at follow up for congenital valvular AS. METHODS: Twenty-five cases with valvular AS, isolated but not treated, were followed for eight years (range: 0.14-18.8 years). Clinical and complementary tests (electrocardiography, X-radiography) were undertaken. The gradient anatomy and function were measured using M-mode, two-dimensional, and Doppler echocardiography. RESULTS: No significant changes were noted in symptoms or at physical examination. Signs of cardiac enlargement were decreased (p < 0.001), and the functional status and gradient remained stable during the follow up period (mean difference 2.38 mmHg; p = 0.74). The relationship between gradient and age showed a slowly increasing trend (r = 0.20). CONCLUSION: The trend in gradient confirmed the stable nature of mild AS. Patients in whom gradients were < 40 mmHg at the time of diagnosis remained stable and required no treatment. Subsequent follow up control and clinical management of these patients may be performed at intervals of two years, or more.
Julio Ardura; Carmen Gonzalez; Jesus Andres
Related Documents :
2764825 - Ascending aortic aneurysms associated with aortic valve regurgitation: st vincent's hos...
17503515 - Feasibility of transcatheter intervention for severe aortic stenosis in patients >or=90...
17243505 - Medium-term results from pulmonary autografts after the ross procedure in children and ...
19255775 - Open versus endovascular repair of acute aortic transections--a non-randomized single-c...
19348375 - Management of the prosthetic vascular graft infections--the influence of predictive fac...
24222905 - A comparison between tube surgery, nd:yag laser and diode laser cyclophotocoagulation i...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of heart valve disease     Volume:  15     ISSN:  0966-8519     ISO Abbreviation:  J. Heart Valve Dis.     Publication Date:  2006 Jan 
Date Detail:
Created Date:  2006-02-16     Completed Date:  2006-09-12     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9312096     Medline TA:  J Heart Valve Dis     Country:  England    
Other Details:
Languages:  eng     Pagination:  1-4     Citation Subset:  IM    
Pediatric Cardiology, University Hospital, Facultad de Medicina, Valladolid, Spain.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Age Factors
Aortic Valve Insufficiency / congenital,  diagnosis,  pathology,  physiopathology
Aortic Valve Stenosis / congenital,  diagnosis,  pathology*,  physiopathology*
Child, Preschool
Disease Progression
Echocardiography, Doppler
Follow-Up Studies
Heart Rate
Prospective Studies
Radiography, Thoracic
Severity of Illness Index
Stroke Volume
Ventricular Function, Left

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  [Study of oculomotor disorders in spinocerebellar ataxia genotype].
Next Document:  Impact of mechanical and biological aortic valve replacement on coronary perfusion: a prospective, r...