Document Detail

Does maternal knowledge impact blood phenylalanine concentration in Turkish children with phenylketonuria?
MedLine Citation:
PMID:  18581253     Owner:  NLM     Status:  In-Data-Review    
The aim of this study was to compare the level of maternal knowledge and the blood phenylalanine (Phe) control in phenylketonuria (PKU; OMIM 261600). The study was conducted on 144 children (81 boys, 63 girls) with PKU, aged between 1 and 15 years, at Hacettepe University Ihsan Dogramaci Children's Hospital, Metabolism and Nutrition Unit. All subjects were treated with a low-Phe diet using a Phe-exchange system. A 20-question multiple-choice questionnaire was applied to the mothers to determine their knowledge about PKU and its dietary treatment. Questions in the test consisted of the knowledge about the disease (6 questions), general dietary knowledge (14 questions) and knowledge about specific exchange within the dietary questions (6 questions). The median blood Phe concentration for the previous 3-year period was used as an indicator of metabolic control. Eighty-seven children had a median blood Phe concentration above the MRC Working Party Guidelines. There was a negative correlation between maternal knowledge about exchange and median blood Phe concentration in the child (p<0.05). Maternal knowledge about a standard 15 mg Phe exchange system is correlated with dietary compliance as measured by blood Phe concentrations in our subjects. We would like to implement an easier method of measuring Phe exchanges to improve dietary knowledge in the mothers.
H Gokmen Ozel; T Kucukkasap; G Koksal; H S Kalkanoglu Sivri; A Dursun; A Tokatli; T Coskun
Related Documents :
10149513 - Development and current status of a new intracorporeal membrane oxygenator (ivox).
6755823 - Use of whole blood exchange transfusion to supply neutrophils to septic, neutropenic ne...
7768033 - Historical perspective of cardiorenal integration.
Publication Detail:
Type:  Journal Article     Date:  2008-06-27
Journal Detail:
Title:  Journal of inherited metabolic disease     Volume:  31 Suppl 2     ISSN:  1573-2665     ISO Abbreviation:  J. Inherit. Metab. Dis.     Publication Date:  2008 Dec 
Date Detail:
Created Date:  2011-09-06     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7910918     Medline TA:  J Inherit Metab Dis     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  213-7     Citation Subset:  IM    
Faculty of Health Sciences, Department of Nutrition and Dietetics, Hacettepe University, 06100, Ankara, Turkey,
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Sugar-driven prebiotic synthesis of 3,5(6)-dimethylpyrazin-2-one: a possible nucleobase of a primiti...
Next Document:  Magnetic resonance evaluation of liver and myocardial iron deposition in thalassemia intermedia and ...