Document Detail

Does laparoscopic removal of nonendometriotic benign ovarian cysts affect ovarian reserve?
MedLine Citation:
PMID:  16521684     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: The objective of this study was to investigate whether laparoscopic excision of nonendometriotic benign ovarian cysts is associated with a significant injury to ovarian reserve. METHODS: Women selected for IVF-ICSI cycles who previously underwent laparoscopic excision of a monolateral nonendometriotic benign ovarian cyst were retrospectively identified. The operated ovary and the contralateral intact gonad of the same patient were compared in term of basal ovarian volume before initiating ovarian stimulation and number of dominant follicles at the time of human chorionic gonadotropin administration. Non-parametric Wilcoxon Rank test was used to investigate differences between the two ovaries. RESULTS: Seventeen cases were recruited. The numbers of dominant follicles were 4.6 +/- 2.5 and 2.7 +/- 2.4 in the control ovary and in the previously operated ovary, respectively (p = 0.01). This drop corresponded to a mean reduction of 42% (95% confidence interval: 10-74%). Basal volumes of the intact and the operated gonads were 5.7 +/- 3.3 and 3.4 +/- 2.3 cm3 respectively (p = 0.01), corresponding to a mean reduction of 39% (95% confidence interval: 12-66%). CONCLUSIONS: Laparoscopic excision of nonendometrioid benign ovarian cysts is associated with a significant injury to ovarian reserve.
Edgardo Somigliana; Guido Ragni; Mirco Infantino; Francesca Benedetti; Mariangela Arnoldi; Pier Giorgio Crosignani
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Acta obstetricia et gynecologica Scandinavica     Volume:  85     ISSN:  0001-6349     ISO Abbreviation:  Acta Obstet Gynecol Scand     Publication Date:  2006  
Date Detail:
Created Date:  2006-03-08     Completed Date:  2006-04-11     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0370343     Medline TA:  Acta Obstet Gynecol Scand     Country:  Denmark    
Other Details:
Languages:  eng     Pagination:  74-7     Citation Subset:  IM    
Infertility Unit, Department of Obstetrics and Gynecology, Ospedale Maggiore Policlinico, Mangiagalli and Regina Elena, Milan, Italy.
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MeSH Terms
Chorionic Gonadotropin / administration & dosage
Fertility Agents, Female / administration & dosage
Fertilization in Vitro
Ovarian Cysts / surgery*
Ovarian Follicle / physiology*
Ovulation Induction
Retrospective Studies
Reg. No./Substance:
0/Chorionic Gonadotropin; 0/Fertility Agents, Female

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