Document Detail


Does it matter how we feed premature babies?
MedLine Citation:
PMID:  3328120     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The multiplicity of dietary regimes available for low birthweight infants is a measure of clinical uncertainty in this field. The reasons for this persisting uncertainty are analysed: few studies have examined whether early diet matters in terms of clinical outcome; instead, management decisions have been based on short-term 'physiological' studies on nutrient accretion, growth and metabolism. Data from this Unit's multicentre outcome trials on nearly 1000 preterm infants, randomly assigned to early diet, are used to demonstrate that whilst diet influences many aspects of the infants 'physiology' in the short term, such physiological responses have limited value in predicting clinical outcome. Preliminary data from the early follow-up of this cohort to 18 months post-term suggest that the diet used in the neonatal period may have persisting consequences in terms of motor and mental development and growth. The longer-term significance of these findings is being investigated.
Authors:
A Lucas
Publication Detail:
Type:  Clinical Trial; Journal Article; Review    
Journal Detail:
Title:  Nutrition and health     Volume:  5     ISSN:  0260-1060     ISO Abbreviation:  Nutr Health     Publication Date:  1987  
Date Detail:
Created Date:  1988-05-03     Completed Date:  1988-05-03     Revised Date:  2012-02-23    
Medline Journal Info:
Nlm Unique ID:  8306569     Medline TA:  Nutr Health     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  197-202     Citation Subset:  IM    
Affiliation:
University of Cambridge, England.
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MeSH Terms
Descriptor/Qualifier:
Clinical Trials as Topic
Diet
Humans
Infant Food
Infant Nutritional Physiological Phenomena*
Infant, Newborn
Infant, Premature / physiology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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