Document Detail

Does inflammatory linear verrucous epidermal nevus represent a segmental type 1/type 2 mosaic of psoriasis?
MedLine Citation:
PMID:  16484814     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: A 6-year-old girl with a symmetric linear eruption on both of her legs, clinically and histologically resembling inflammatory linear verrucous epidermal nevus (ILVEN) or linear psoriasis (LP), with concomitant psoriasis of the guttata type and a positive family history of psoriasis is presented. The questions as to whether LP actually exists and ILVEN represents a distinct entity are still under debate. OBJECTIVE AND METHODS: The recent literature concerning case reports of ILVEN and LP is reviewed. RESULTS: Case reports of ILVEN and LP can be subdivided into four different groups: (1) ILVEN with or without concomitant psoriasis, only in part reacting to antipsoriatic treatment, (2) ILVEN without concomitant psoriasis, (3) LP with concomitant psoriasis vulgaris, with both groups 2 and 3 reacting successfully to antipsoriatic treatment, and (4) LP without concomitant psoriasis vulgaris and with no family history of psoriasis (very rarely reported). CONCLUSION: It is hypothesized that inflammatory linear verrucous eruption besides nevoid psoriasis/LP represents a further segmental type 1/type 2 mosaic of psoriasis which, if a (verrucous) epidermal nevus exists, shows a high affinity of occurrence in close context to such a nevus. Heritability is thought to be possible.
Thomas Hofer
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Dermatology (Basel, Switzerland)     Volume:  212     ISSN:  1018-8665     ISO Abbreviation:  Dermatology (Basel)     Publication Date:  2006  
Date Detail:
Created Date:  2006-02-17     Completed Date:  2006-06-15     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9203244     Medline TA:  Dermatology     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  103-7     Citation Subset:  IM    
Copyright Information:
Copyright (c) 2006 S. Karger AG, Basel.
Dermatology and Venereology FMH, Winkelriedstrasse 10, CH-5430 Wettingen, Switzerland.
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MeSH Terms
Administration, Topical
Child, Preschool
Dermatologic Agents / administration & dosage,  therapeutic use
Diagnosis, Differential
Dihydroxycholecalciferols / administration & dosage,  therapeutic use
Follow-Up Studies
Nevus / diagnosis*
Psoriasis / classification,  diagnosis*,  drug therapy
Skin Neoplasms / diagnosis*
Reg. No./Substance:
0/Dermatologic Agents; 0/Dihydroxycholecalciferols; 0/Ointments; 60965-80-2/1 alpha,24-dihydroxyvitamin D3
Comment In:
Dermatology. 2006;212(2):101-2   [PMID:  16484813 ]

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