Document Detail


DOES IMPROVED ACCESS AND GREATER CHOICE OF NICOTINE REPLACEMENT THERAPY AFFECT SMOKING CESSATION SUCCESS? FINDINGS FROM A RANDOMISED CONTROLLED TRIAL.
MedLine Citation:
PMID:  21371155     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Aims:  To determine the effect of offering smokers who want to quit easy access to nicotine replacement therapy (NRT), a period of familiarisation, and choice of product, on smoking abstinence at six months. Design:  Single-blind, randomised controlled trial. Setting:  New Zealand. Participants:  1,410 adult smokers who called the national Quitline for quitting support were randomised to usual Quitline care or a box containing different NRT products (patch, gum, inhaler, sublingual tablet, oral pouch) to try for a week prior to quitting, and then to choose one or two of these products for eight weeks use. Measurements:  The primary outcome was seven-day point prevalence smoking abstinence six months after quit day. Secondary outcomes included continuous abstinence, cigarette consumption, withdrawal, NRT choice and serious adverse events at one and three weeks and three and six months. Findings:  No differences in six-month quit rates (seven-day point prevalence or continuous abstinence) were observed between the groups. However, smokers allocated to the intervention group were more likely to have quit smoking at three months (self-reported point prevalence, RR = 1.17, 95% CI = 1.02, 1.35, p = 0.03), had a longer time to relapse (median 70 days versus 28 days, p < 0.01) and used significantly more NRT. The selection box concept was highly acceptable to users, with the patch and inhaler combination the most popular choice (34%). Conclusions:  In terms of smoking abstinence at six months, offering smokers who want to quit free access to a wide range of NRT, including a one week period of familiarisation and choice of up to two products, appears no different to offering reduced cost and choice of NRT, with no familiarisation period.
Authors:
Natalie Walker; Colin Howe; Chris Bullen; Michele Grigg; Marewa Glover; Hayden McRobbie; Murray Laugesen; Joy Jiang; Mei-Hua Chen; Robyn Whittaker; Anthony Rodgers
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-3-3
Journal Detail:
Title:  Addiction (Abingdon, England)     Volume:  -     ISSN:  1360-0443     ISO Abbreviation:  -     Publication Date:  2011 Mar 
Date Detail:
Created Date:  2011-3-4     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9304118     Medline TA:  Addiction     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
© 2011 The Authors, Addiction © 2011 Society for the Study of Addiction.
Affiliation:
Clinical Trials Research Unit, School of Population Health, The University of Auckland, Private Bag 92019, Auckland, NZ Clinical Trials Research Unit, School of Population Health, The University of Auckland, Private Bag 92019, Auckland, NZ Clinical Trials Research Unit, School of Population Health, The University of Auckland, Private Bag 92019, Auckland, NZ Formally of The Quit Group, PO Box 12605, Wellington, NZ, now Litmus, Wellington, NZ Centre for Tobacco Control Research, Social & Community Health, School of Population Health, The University of Auckland, Private Bag 92019, Auckland, NZ Formally of Clinical Trials Research Unit, School of Population Health, The University of Auckland, Private Bag 92019, Auckland, NZ; now Queen Mary University of London, Wolfson Institute of Preventive Medicine, Barts and The London School of Medicine and Dentistry, Charterhouse Square, London, EC1M 6BQ, England. Health NZ Ltd., 36 Winchester St, Lyttelton, Christchurch 8082, NZ Clinical Trials Research Unit, School of Population Health, The University of Auckland, Private Bag 92019, Auckland, NZ Formally of Clinical Trials Research Unit, School of Population Health, The University of Auckland, Private Bag 92019, Auckland, NZ; now Eli Lilly and Company (NZ) Limited Clinical Trials Research Unit, School of Population Health, The University of Auckland, Private Bag 92019, Auckland, NZ Formally of Clinical Trials Research Unit, School of Population Health, The University of Auckland, Private Bag 92019, Auckland, NZ; now The George Institute for International Health, PO Box 201, Missenden Rd, NSW 2050, Australia.
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