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Does hydronephrosis predict the presence of severe vesicoureteral reflux?
MedLine Citation:
PMID:  22735979     Owner:  NLM     Status:  Publisher    
We hypothesized that, in patients with vesicoureteral reflux (VUR) grade IV or V, hydronephrosis will likely be found, if the patient has a full bladder during the renal ultrasound examination. Eight hundred thirty-seven patients were included in the study. Patients ranged in age from <1 month to 18.7 years, with a median age of 1.3 years. Five hundred sixty-nine were female and 268 were male. In this retrospective study, each patient underwent a voiding cystourethrogram (VCUG) and a renal ultrasound examination. The presence of hydronephrosis and bladder filling status in 131 renal units with VUR grade IV or V was evaluated. Sensitivity and specificity for hydronephrosis to detect the presence of VUR grades IV and V were 60 and 92 %, respectively. Positive predictive value and negative predictive value were 74 and 87 %, respectively. Odds ratios for the relationship between hydronephrosis and severe VUR was significant (p = 0.046). Conclusion: In patients with grade IV or V VUR, hydronephrosis will be observed in the presence of a full bladder. Therefore, a renal ultrasound could be considered a screening test to decide on performing a VCUG.
Husam A Abdulnour; Jonathan L Williams; John A Kairalla; Eduardo H Garin
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-6-27
Journal Detail:
Title:  European journal of pediatrics     Volume:  -     ISSN:  1432-1076     ISO Abbreviation:  -     Publication Date:  2012 Jun 
Date Detail:
Created Date:  2012-6-27     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7603873     Medline TA:  Eur J Pediatr     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Pediatric Nephrology Division, College of Medicine, University of Florida, P.O. Box 100296, Gainesville, FL, 32610, USA.
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