| Does the historical literature on encephalitis lethargica support a simple (direct) relationship with postencephalitic Parkinsonism? | |
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MedLine Citation:
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PMID: 20629127 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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This article and the subsequent one suggest that the currently accepted view of a simplistic (direct) relationship between encephalitis lethargica (EL) and postencephalitic Parkinsonism (PEP) is based on a incomplete evaluation of the epidemic period literature. In this article we provide a detailed analysis of the literature from the period that demonstrates that Parkinsonism was not initially part of acute EL symptomatology, that PEP was not typically the prevailing type of chronic EL and that oculogyric crises were never part of acute EL symptomatology and not initially associated with PEP. The second paper uses these finding, and also examines the clinical justifications for concluding that all patients with PEP had prior acute episodes of EL, to reevaluate the presumed direct etiologic relationship between EL and PEP. |
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Authors:
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Joel A Vilensky; Sid Gilman; Sherman McCall |
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Publication Detail:
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Type: Historical Article; Journal Article; Research Support, Non-U.S. Gov't; Review |
Journal Detail:
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Title: Movement disorders : official journal of the Movement Disorder Society Volume: 25 ISSN: 1531-8257 ISO Abbreviation: Mov. Disord. Publication Date: 2010 Jul |
Date Detail:
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Created Date: 2010-07-26 Completed Date: 2010-11-04 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8610688 Medline TA: Mov Disord Country: United States |
Other Details:
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Languages: eng Pagination: 1124-30 Citation Subset: IM |
Affiliation:
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Department of Anatomy and Cell Biology, Indiana University School of Medicine, Fort Wayne, Indiana 46805, USA. vilensk@ipfw.edu |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Encephalitis
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complications*,
history History, 20th Century Humans Medicine in Literature* Parkinson Disease, Postencephalitic / complications*, history |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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