| Does glucagon enhance opacification of the bile ducts during intravenous cholangiography? An experimental study in dogs. | |
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MedLine Citation:
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PMID: 7076434 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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To determine the rational for the ability of glucagon to enhance opacification of the bile ducts during intravenous cholangiography, which has been claimed in recent clinical reports, experiments were performed in dogs which had had Thomas cannulas inserted. A constant step-wise infusion of iodipamide was administered with or without a bolus injection and constant infusion of glucagon. At every infusion rate of iodipamide the biliary concentration of the contrast agent was less when glucagon was administered. Glucagon caused a choleresis, but had no effect on the rate of excretion of iodipamide. It is concluded that the theory that glucagon is of value to improve opacification of the bile ducts during intravenous cholangiography is unlikely to be confirmed by further clinical trials. |
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Authors:
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R N Berk; J L Barnhart; G D Nazareno; N D Brourman; L Flamm |
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Publication Detail:
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Type: Journal Article; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: Investigative radiology Volume: 17 ISSN: 0020-9996 ISO Abbreviation: Invest Radiol Publication Date: 1982 Jan-Feb |
Date Detail:
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Created Date: 1982-07-08 Completed Date: 1982-07-08 Revised Date: 2009-11-11 |
Medline Journal Info:
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Nlm Unique ID: 0045377 Medline TA: Invest Radiol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 50-2 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Bile Acids and Salts / secretion Cholangiography* Dogs Glucagon / diagnostic use, pharmacology* Iodipamide / diagnostic use |
| Grant Support | |
ID/Acronym/Agency:
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PHS-AM 21620-03/AM/NIADDK NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/Bile Acids and Salts; 606-17-7/Iodipamide; 9007-92-5/Glucagon |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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