Document Detail

Does food intolerance play a role in recurrent respiratory papillomatosis?
MedLine Citation:
PMID:  22311847     Owner:  NLM     Status:  In-Data-Review    
BACKGROUND: The purpose of this study is to evaluate the potential role of food intolerances in the management of recurrent respiratory papillomatosis (RRP).
METHODS: This is a retrospective case review of 4 pediatric patients with RRP. All of the patients, cared for by the primary author between 2005 and 2010, were managed using microdebrider resection, intralesional injection of cidofovir, and required multiple surgeries. Skin prick test (SPT) and/or radioallergosorbent test (RAST) were obtained for 2 patients. Oral food challenge was utilized in all 4 patients.
RESULTS: Standard SPT and RAST did not identify any immunoglobulin E (IgE)-based allergens. A detailed medical history followed by an oral food challenge was successful at identifying food intolerances in all 4 patients. When specific food elimination was implemented in these patients' treatments in addition to microdebrider resection and cidofovir injection, statistically significant long-term remissions were achieved.
CONCLUSION: Food intolerance and its impact on RRP and immune dysfunction deserve further investigation and may benefit some patients with RRP. © 2011 ARS-AAOA, LLC.
Nalin J Patel; Ali Jenzarli
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Publication Detail:
Type:  Journal Article     Date:  2011-09-15
Journal Detail:
Title:  International forum of allergy & rhinology     Volume:  2     ISSN:  2042-6984     ISO Abbreviation:  Int Forum Allergy Rhinol     Publication Date:  2012 Jan 
Date Detail:
Created Date:  2012-02-07     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101550261     Medline TA:  Int Forum Allergy Rhinol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  85-8     Citation Subset:  IM    
Copyright Information:
Copyright © 2011 American Rhinologic Society-American Academy of Otolaryngic Allergy, LLC.
Tampa Ear Nose and Throat Associates, Tampa, FL.
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