| Does follicle-stimulating hormone or pregnant mare serum gonadotrophin influence testicular blood flow in rats? | |
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MedLine Citation:
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PMID: 1516985 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Treatment of adult rats with 25 iu follicle-stimulating hormone (FSH) did not influence testicular blood flow, serum testosterone, vasomotion or intravascular leucocyte concentration at 6, 12 and 24 h after treatment. Treatment of adult rats with 50 iu pregnant mare serum gonadotrophin (PMSG) resulted in a two-fold increase in testicular blood flow at 24 h, and an increase in interstitial fluid volume at 36 h after treatment. This PMSG-induced increase in blood flow did not occur in Leydig cell-depleted animals, suggesting that the effect on blood flow is mediated via the Leydig cells. PMSG injection stimulated testosterone secretion but it did not influence vasomotion, and it only marginally increased the secretion of leucotactic factors in the testis. The present study suggests that FSH has no apparent effects on testicular blood flow and that the effects of PMSG (a hormone with both FSH and LH-like activity) is mediated via stimulation of the Leydig cells. |
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Authors:
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A Bergh; J E Damber; L Lieu; A Widmark |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: International journal of andrology Volume: 15 ISSN: 0105-6263 ISO Abbreviation: Int. J. Androl. Publication Date: 1992 Aug |
Date Detail:
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Created Date: 1992-10-07 Completed Date: 1992-10-07 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8000141 Medline TA: Int J Androl Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 365-71 Citation Subset: IM |
Affiliation:
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Department of Anatomy, University of Umeå, Sweden. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Follicle Stimulating Hormone / pharmacology* Gonadotropins, Equine / pharmacology* Leydig Cells / physiology Male Rats Rats, Inbred Strains Regional Blood Flow / drug effects Testis / blood supply*, drug effects Testosterone / blood |
| Chemical | |
Reg. No./Substance:
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0/Gonadotropins, Equine; 58-22-0/Testosterone; 9002-68-0/Follicle Stimulating Hormone |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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