Document Detail


Does exogenous coenzyme Q10 affect aerobic capacity in endurance athletes?
MedLine Citation:
PMID:  9286743     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The effect of orally supplemented coenzyme Q10 (CoQ10) on plasma CoQ10 concentration and aerobic capacity in endurance athletes was evaluated. Eighteen volunteer male road cyclists and triathletes, 8 in a CoQ10 supplementation group (QG) and 10 in a placebo group (PG), successfully completed the experimental protocol. Subjects were evaluated during and following graded cycling exercise tests, which were performed before and after 28 days of supplementation with 1 mg.kg-1.day-1 of CoQ10 or placebo. The presupplementation plasma CoQ10 concentration was significantly increased from 0.91 +/- 0.13 microgram.ml-1 to 1.97 +/- 0.27 microgram.ml-1 in QG following supplementation (p < .05). However, the CoQ10 supplementation regime had no consistently significant effect on oxygen uptake, anaerobic and respiratory compensation thresholds, blood lactate, glucose and triglyceride kinetics, heart rate, and blood pressure during and after graded cycling to exhaustion.
Authors:
S B Weston; S Zhou; R P Weatherby; S J Robson
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Publication Detail:
Type:  Clinical Trial; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  International journal of sport nutrition     Volume:  7     ISSN:  1050-1606     ISO Abbreviation:  Int J Sport Nutr     Publication Date:  1997 Sep 
Date Detail:
Created Date:  1997-10-08     Completed Date:  1997-10-08     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  9307702     Medline TA:  Int J Sport Nutr     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  197-206     Citation Subset:  IM    
Affiliation:
School of Exercise Science & Sport Management, Southern Cross University, Lismore, Australia.
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MeSH Terms
Descriptor/Qualifier:
Administration, Oral
Adolescent
Adult
Analysis of Variance
Blood Glucose
Coenzymes
Double-Blind Method
Exercise / physiology
Exercise Tolerance / drug effects*
Humans
Lactates / blood
Male
Oxygen Consumption
Sports*
Ubiquinone / administration & dosage,  analogs & derivatives*,  blood,  pharmacology
Chemical
Reg. No./Substance:
0/Blood Glucose; 0/Coenzymes; 0/Lactates; 1339-63-5/Ubiquinone; 303-98-0/coenzyme Q10

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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