| Does dobutamine improve ventricular function in dogs with regional myocardial dysfunction? | |
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MedLine Citation:
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PMID: 12088936 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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IMPLICATIONS: We examined the effect of systemic dobutamine on regional wall motion abnormalities (RWMAs) induced by intracoronary esmolol infusion in eight anesthetized dogs. Esmolol dilated the heart and decreased regional synchrony of contraction. Dobutamine restored cardiac function but failed to correct the asynchrony of regional contraction caused by esmolol-induced RWMAs. |
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Authors:
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David P Strum; Michael R Pinsky |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S. |
Journal Detail:
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Title: Anesthesia and analgesia Volume: 95 ISSN: 0003-2999 ISO Abbreviation: Anesth. Analg. Publication Date: 2002 Jul |
Date Detail:
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Created Date: 2002-06-28 Completed Date: 2002-07-23 Revised Date: 2013-05-20 |
Medline Journal Info:
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Nlm Unique ID: 1310650 Medline TA: Anesth Analg Country: United States |
Other Details:
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Languages: eng Pagination: 19-25, table of contents Citation Subset: AIM; IM |
Affiliation:
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Department of Anesthesiology and Critical Care Medicine, Kingston General Hospital, Queen's University, 76 Stuart Street, Kingston, Ontario K7L 2V7, Canada. strumd@post.queensu.ca |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adrenergic beta-Antagonists
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pharmacology Animals Blood Pressure / drug effects Cardiomyopathies / physiopathology* Cardiotonic Agents / pharmacology* Dobutamine / pharmacology* Dogs Dose-Response Relationship, Drug Heart Conduction System / drug effects Heart Rate / drug effects Infusions, Intravenous Myocardial Contraction / drug effects Propanolamines / pharmacology Stroke Volume / physiology Ventricular Function / drug effects* Ventricular Function, Left / drug effects |
| Chemical | |
Reg. No./Substance:
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0/Adrenergic beta-Antagonists; 0/Cardiotonic Agents; 0/Propanolamines; 34368-04-2/Dobutamine; MDY902UXSR/esmolol |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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