Document Detail

Does deep brain stimulation induce apathy in Parkinson's disease?
MedLine Citation:
PMID:  18508589     Owner:  NLM     Status:  MEDLINE    
Chronic deep brain stimulation (DBS) is an important therapeutic advancement for the treatment of motor symptoms in Parkinson's disease (PD). However, its effects on non-motor symptoms are not well understood. Several studies have reported motivational disturbances and apathy after DBS surgery. Recent studies are beginning to more carefully examine the relationship between DBS and apathy. This review summarizes and evaluates the current state of the literature on apathy after DBS surgery, discusses methodological limitations in the literature, and makes suggestions for future research.
Lindsey Kirsch-Darrow; Ania Mikos; Dawn Bowers
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't     Date:  2008-05-01
Journal Detail:
Title:  Frontiers in bioscience : a journal and virtual library     Volume:  13     ISSN:  1093-4715     ISO Abbreviation:  Front. Biosci.     Publication Date:  2008  
Date Detail:
Created Date:  2008-05-29     Completed Date:  2008-09-19     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9709506     Medline TA:  Front Biosci     Country:  United States    
Other Details:
Languages:  eng     Pagination:  5316-22     Citation Subset:  IM    
University of Florida Department of Clinical and Health Psychology, P.O. Box 100165, Gainesville, FL 32610, USA.
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MeSH Terms
Cognition Disorders / etiology
Deep Brain Stimulation / adverse effects*
Depression / etiology*
Parkinson Disease / complications,  psychology,  therapy*
Grant Support

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