Document Detail


Does the consumption of amylase-containing gruels impact on the energy intake and growth of Congolese infants?
MedLine Citation:
PMID:  12740074     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: To assess the effect of the incorporation of amylase in maize-based flours prepared as gruels on the energy intake and growth of Congolese infants. DESIGN: A randomised controlled trial. At 18 weeks of age, infants were randomised into either an intervention group, where they were provided with a maize/soya-based flour that contained amylase, or a control group, where they were provided with a similar flour that did not contain amylase. SETTING: Urban borough of Poto-Poto in Brazzaville, The Congo. SUBJECTS: Eighty infants (40 in each group) were randomised into intervention and control groups. Three infants in the intervention group and two controls subsequently dropped out. RESULTS: At 24 weeks, the addition of amylase resulted in a significant increase in energy intake (in kJ kg-1 day-1) from gruels without affecting breast milk consumption. In contrast, total energy intake (in kJ kg-1 day-1) did not differ significantly between groups (P= 0.08). After adjustment for morbidity and previous growth, infants in the intervention group showed better growth in length during the trial (+0.22 cm month-1; P= 0.04), especially between 24 and 31 weeks of age (+0.51 cm month-1; P< 0.01). There were no differences in weight velocity between groups. CONCLUSIONS: The findings of this study suggest that the consumption of amylase-treated gruels allows an increase in energy intake from these gruels without affecting breast milk consumption but has no impact on total daily energy intake. However, if started after 6 months, it could be effective in preventing faltering of infant linear growth.
Authors:
M Moursi; F Mbemba; S Trèche
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Publication Detail:
Type:  Clinical Trial; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Public health nutrition     Volume:  6     ISSN:  1368-9800     ISO Abbreviation:  Public Health Nutr     Publication Date:  2003 May 
Date Detail:
Created Date:  2003-05-12     Completed Date:  2003-10-30     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9808463     Medline TA:  Public Health Nutr     Country:  England    
Other Details:
Languages:  eng     Pagination:  249-58     Citation Subset:  IM    
Affiliation:
Nutrition, Alimentation, Sociétés Research Unit, Institut de Recherche pour le Développement, UR106, BP 64501, F-34394 Montpellier Cedex 5, France.
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MeSH Terms
Descriptor/Qualifier:
Amylases / administration & dosage*
Anthropometry
Breast Feeding
Cereals* / enzymology
Congo
Energy Intake*
Female
Flour
Growth / physiology*
Humans
Infant
Infant Food
Male
Nutritive Value
Weaning*
Chemical
Reg. No./Substance:
EC 3.2.1.-/Amylases

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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