Document Detail

Does combination of antegrade and retrograde cardioplegia reduce coronary artery bypass grafting-related conduction defects?
MedLine Citation:
PMID:  17060042     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Conduction disorders appearing after coronary artery bypass surgery (CABG) may have many different causes. In this study, we evaluated the postoperative conduction disorders after CABG with respect to the ante-grade blood cardioplegia and ante-grade plus continuous retrograde cardioplegia delivery methods. MATERIALS AND METHODS: This retrospective study included 1824 patients undergoing CABG between January 2001 and December 2005. There were 694 female patients (38%) and 1130 male patients (62%). Myocardial protection was done by isothermic hyperkalemic blood cardioplegia. Patents in Group 1 (n = 704) were operated on using only intermittent antegrade cardioplegia and those in group 2 (n = 1120) were operated on using the antegrade plus retrograde continuous cardioplegia. The postoperative occurrences of a new right bundle branch block, left anterior hemiblock, left posterior hemiblock, left bundle branch block, or third-degree atrioventricular block were evaluated and compared. RESULTS: Total mortality rate was 1.6% (29 patients) without significant difference between the groups. The preoperative and perioperative characteristics were statistically similar in the groups. The occurrence of conduction disorders was significantly higher in group 1 (P = .006, 55 versus 52 patients). The analysis of the patients with conduction disorders showed a significantly increased mortality rate (P < .001) in addition to a significantly increased period of intensive care unit follow-up and duration of postoperative hospitalization (P <.001). CONCLUSION: The present study demonstrated that the perioperative occurrence of conduction disorders after CABG was decreased by antegrade controlled and retrograde continuous combination cardioplegia.
Cengiz Bolcal; Bilgin Emrecan; Hakan Bingöl; Mehmet Fatih Ayik; Faruk Cingöz; Vedat Yildirim; Erkan Kuralay; Ufuk Demirkiliç; Selim Kiliç; Harun Tatar
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The heart surgery forum     Volume:  9     ISSN:  1522-6662     ISO Abbreviation:  Heart Surg Forum     Publication Date:  2006  
Date Detail:
Created Date:  2006-10-24     Completed Date:  2006-12-13     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100891112     Medline TA:  Heart Surg Forum     Country:  United States    
Other Details:
Languages:  eng     Pagination:  E866-70     Citation Subset:  IM    
Department of Cardiovascular Surgery, Gulhane Military Medical Academy, Ankara, Turkey.
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MeSH Terms
Coronary Artery Bypass / mortality*
Coronary Vessels
Heart Arrest, Induced / mortality*
Heart Block / mortality*
Middle Aged
Retrospective Studies
Risk Assessment / methods*
Risk Factors
Survival Analysis
Survival Rate
Turkey / epidemiology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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