Document Detail

Does cold air affect exercise capacity and dyspnea in stable chronic obstructive pulmonary disease?
MedLine Citation:
PMID:  8449053     Owner:  NLM     Status:  MEDLINE    
Cold air may worsen asthmatic bronchoconstriction but can lessen breathlessness in normal individuals. Patients with COPD sometimes report improvement in their dyspnea in cold weather. We examined the effect of breathing cold air on exercise tolerance and the perception of breathlessness in 19 patients with stable COPD (age [+/- SD], 63 +/- 6 years; FEV1, 0.99 +/- 0.28 L) in a randomized open study. Patients exercised on a cycle ergometer breathing either room or cold air (-13 degrees C), breathlessness being assessed by Borg scaling. Peak exercise performance improved when breathing cold air (mean +/- SE), 46 +/- 6 W compared with 37 +/- 7 W (p < 0.05) while end-exercise breathlessness fell from 4.6 +/- 0.4 compared with 4.1 +/- 0.5 (p < 0.05) when breathing cold air. End-exercise ETCO2 was higher breathing cold air (6.1 +/- 0.3 kPa compared with 5.5 +/- 0.3 kPa) (p < 0.005). There was no difference in breathlessness at equivalent levels of ventilation. Cold air reduces breathlessness in COPD, probably by inducing relative hypoventilation.
D P Spence; D R Graham; J Ahmed; K Rees; M G Pearson; P M Calverley
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Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  Chest     Volume:  103     ISSN:  0012-3692     ISO Abbreviation:  Chest     Publication Date:  1993 Mar 
Date Detail:
Created Date:  1993-04-09     Completed Date:  1993-04-09     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  0231335     Medline TA:  Chest     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  693-6     Citation Subset:  AIM; IM    
Aintree Chest Centre, Liverpool, England.
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MeSH Terms
Cold Temperature*
Dyspnea / physiopathology*
Exercise Test
Exercise Tolerance / physiology*
Lung Diseases, Obstructive / physiopathology*
Middle Aged
Respiratory Function Tests / methods
Respiratory Mechanics / physiology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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