Document Detail

Does circumcision influence recurrences in herpes genitalis?
MedLine Citation:
PMID:  19915236     Owner:  NLM     Status:  MEDLINE    
BACKGROUND AND AIMS: The effect of therapeutic circumcision in men for preventing recurrences of herpes genitalis remains largely unelucidated despite its well documented albeit conflicting role in reducing the risk of acquiring sexually transmitted infections, including genital herpes. METHODS: Twenty volunteer adult males with a history of recurrent herpes genitalis were included in the study after informed consent and circumcision was carried out. Twenty more adult males having recurrent herpes genitalis and registered in the clinic during the same period were selected as controls. All patients and controls were followed-up for recurrences of herpes genitalis. RESULTS AND CONCLUSIONS: Six patients and six controls did not follow-up. Seven patients reported no recurrences during 3-18 years, seven patients had two to six recurrences during 11-27 years of postcircumcision follow-up, 0.0080 (average) recurrences per person per year as compared with 0.20 (average) recurrences per person per year recorded before the circumcision. Two patients had first recurrence 11 years after the circumcision. In comparison, 14 controls had 0.17 (average) recurrences per person per year, comparable with the number of recurrences in uncircumcised patients, and frequently at shorter intervals. Despite being a small study, the circumcision appears to reduce the number of recurrences on an average and evidently prolongs the disease-free period in between two recurrences.
V P Jerath; Vikram K Mahajan
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Publication Detail:
Type:  Controlled Clinical Trial; Journal Article    
Journal Detail:
Title:  Indian journal of dermatology, venereology and leprology     Volume:  75     ISSN:  0973-3922     ISO Abbreviation:  Indian J Dermatol Venereol Leprol     Publication Date:    2009 Nov-Dec
Date Detail:
Created Date:  2009-11-16     Completed Date:  2010-02-05     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7701852     Medline TA:  Indian J Dermatol Venereol Leprol     Country:  India    
Other Details:
Languages:  eng     Pagination:  575-8     Citation Subset:  IM    
Dr. Jerath's Skin and VD Clinic and Allergy Centre, Jalandhar City, Punjab, India.
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MeSH Terms
Circumcision, Male*
Disease-Free Survival
Follow-Up Studies
Herpes Genitalis / epidemiology,  prevention & control*,  surgery*
Recurrence / prevention & control
Risk Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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