Document Detail


Does cardiac function modify left heart opacification with transpulmonary echo contrast agents?
MedLine Citation:
PMID:  10148115     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Dependence of left heart opacification on ventricular function was evaluated for the new transpulmonary echo enhancing agent (SH U 508-A). The contrast agent was injected intravenously in 5 patients with normal cardiac function (ejection fraction [EF] greater than 60% and echocardiographic left ventricular end-diastolic diameter [LVED] less than 56 mm) and in five patients with pathological ventricular function (EF less than 40%, LVED greater than 65 mm). A concentration of 400 mg/mL with dosages of 5, 9, and 16 mL was used in all patients. The visually assessed signal enhancement as well as the videodensitometrically determined peak intensity and duration of signal enhancement did not differ significantly between the two patient groups, while the transit times were markedly prolonged in patients with impaired ventricular function. No significant alteration was found for systemic blood pressure and heart rate. Side effects were transitory and dose related. The noninvasive nature of the procedure and the absence of hemodynamic effects make repeated studies of left ventricular performance with SH U 508-A in patients with varied hemodynamic status possible.
Authors:
H Völler; K Schröder; C Spielberg; A Uhrig; U Wilkenshoff; R Dissmann; R Schlief; R Schröder
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Echocardiography (Mount Kisco, N.Y.)     Volume:  10     ISSN:  0742-2822     ISO Abbreviation:  Echocardiography     Publication Date:  1993 Jan 
Date Detail:
Created Date:  1993-04-22     Completed Date:  1993-04-22     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8511187     Medline TA:  Echocardiography     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  41-7     Citation Subset:  T    
Affiliation:
Department of Cardiopulmonology, Klinikum Steglitz, University of Berlin, Germany.
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MeSH Terms
Descriptor/Qualifier:
Aged
Contrast Media* / adverse effects
Echocardiography / methods*
Humans
Middle Aged
Polysaccharides / diagnostic use*
Pulmonary Circulation
Signal Processing, Computer-Assisted
Ventricular Function, Left*
Chemical
Reg. No./Substance:
0/Contrast Media; 0/Polysaccharides

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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