Document Detail


Does areca nut use lead to dependence?
MedLine Citation:
PMID:  18490113     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: The areca nut is consumed by approximately 10% of the world's population, and its consumption is associated with long-term health risks, with or without tobacco additives. However, it is not known whether its use is associated with a dependence syndrome, as is seen with other psychoactive substances. OBJECTIVE: To examine whether areca nut usage (with or without tobacco additives) could lead to the development of a dependence syndrome. METHODS: Three groups: [a] persons using areca nut preparations without tobacco additives [n=98]; [b] persons using areca nut preparations with tobacco additives [n=44]; and [c] 'Non-users' were systematically assessed using a checklist for the use of areca or areca+tobacco products, patterns of use, presence of a dependence syndrome in users, features of stimulant withdrawal and desired/beneficial effects. RESULTS: 38.8% and 40.8% of the 'areca' group satisfied definitions of current substance-dependence according to DSM-IV and ICD-10 criteria respectively. 79.5% of the areca+tobacco group satisfied criteria for current dependent use according to both DSM-IV and ICD-10 criteria. Both the groups reported a well-delineated withdrawal syndrome and similar attributions for desirable effects of use. CONCLUSION: Areca nut use by itself and more so with tobacco additives, is associated with the development of a dependence syndrome in a substantial numbers of users.
Authors:
Vivek Benegal; Ravi P Rajkumar; Kesavan Muralidharan
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Publication Detail:
Type:  Journal Article     Date:  2008-05-19
Journal Detail:
Title:  Drug and alcohol dependence     Volume:  97     ISSN:  0376-8716     ISO Abbreviation:  Drug Alcohol Depend     Publication Date:  2008 Sep 
Date Detail:
Created Date:  2008-07-14     Completed Date:  2008-12-16     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7513587     Medline TA:  Drug Alcohol Depend     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  114-21     Citation Subset:  IM    
Affiliation:
Deaddiction Centre, Department of Psychiatry, National Institute of Mental Health and Neurosciences, Bangalore, India. vbenegal@gmail.com <vbenegal@gmail.com>
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MeSH Terms
Descriptor/Qualifier:
Adult
Areca / adverse effects*
Data Interpretation, Statistical
Female
Forecasting
Humans
India / epidemiology
Male
Mental Disorders / complications,  psychology
Middle Aged
Psychiatric Status Rating Scales
Public Health
Questionnaires
Socioeconomic Factors
Substance Withdrawal Syndrome / psychology
Substance-Related Disorders / complications,  epidemiology,  psychology*
Tobacco
Tobacco Use Disorder / complications,  epidemiology,  psychology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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