| Does an aortopulmonary shunt before repair of tetralogy of Fallot limit exercise tolerance in long-term survivors? | |
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MedLine Citation:
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PMID: 7582989 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The purpose of this study was to evaluate the impact of an aortopulmonary shunt on exercise capacity in long-term survivors after total repair of tetralogy of Fallot (17.6(2.0) years' follow-up). Submaximal exercise tests, pulmonary function tests, lund diffusion tests for carbon monoxide, two-dimensional and Doppler echocardiography were performed in 12 patients with an aortopulmonary shunt (group A) and in 21 patients (group B) without a shunt before repair. There were no significant differences in two-dimensional and Doppler echocardiographic findings nor in pulmonary function. Group A showed a significantly lower diffusion capacity of the lung for carbon monoxide at rest (66.2(13.0)% versus 84.1(9.5)%; P < 0.01) and at the anaerobic threshold (71.8(11.0)% versus 87.2(9.8)%; P < 0.01) as well as a significantly reduced physical working capacity at ventilatory anaerobic threshold (1.6)(0.32) W/kg versus 2.41(0.43) W/kg; P < 0.01). A negative correlation was observed between the duration of palliative shunts and diffusion capacity of the lung for carbon monoxide at rest at ventilatory anaerobic threshold (r = -0.8635 and -0.9108 respectively). A shunt placed before definitive repair impairs the long-term working capacity, probably by diminishing the diffusion capacity of the lung for carbon monoxide, especially if the shunt is in place for more than 20 months. |
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Authors:
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R Leyh; A Böhle; H H Sievers; A Bernhard |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Cardiovascular surgery (London, England) Volume: 3 ISSN: 0967-2109 ISO Abbreviation: Cardiovasc Surg Publication Date: 1995 Aug |
Date Detail:
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Created Date: 1995-12-06 Completed Date: 1995-12-06 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 9308765 Medline TA: Cardiovasc Surg Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 369-74 Citation Subset: IM |
Affiliation:
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Department of Cardiovascular Surgery, University of Kiel, Germany. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Anaerobic Threshold / physiology Angiography Blood Flow Velocity / physiology Echocardiography Exercise Test* Female Follow-Up Studies Hemodynamics / physiology* Humans Lung / blood supply Male Palliative Care Postoperative Complications / mortality, physiopathology* Pulmonary Diffusing Capacity / physiology* Survival Rate Tetralogy of Fallot / mortality, physiopathology*, surgery |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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