Document Detail

Does alendronate prevent collapse in osteonecrosis of the femoral head?
MedLine Citation:
PMID:  16462451     Owner:  NLM     Status:  MEDLINE    
LEVEL OF EVIDENCE: Therapeutic study, level II (prospective comparative study). See the Guidelines for Authors for a complete description of levels of evidence.
Takashi Nishii; Nobuhiko Sugano; Hidenobu Miki; Jun Hashimoto; Hideki Yoshikawa
Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Clinical orthopaedics and related research     Volume:  443     ISSN:  0009-921X     ISO Abbreviation:  Clin. Orthop. Relat. Res.     Publication Date:  2006 Feb 
Date Detail:
Created Date:  2006-02-07     Completed Date:  2006-03-30     Revised Date:  2013-05-20    
Medline Journal Info:
Nlm Unique ID:  0075674     Medline TA:  Clin Orthop Relat Res     Country:  United States    
Other Details:
Languages:  eng     Pagination:  273-9     Citation Subset:  AIM; IM    
Department of Orthopaedic Surgery, Osaka University Medical School, Osaka, Japan.
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MeSH Terms
Alendronate / therapeutic use*
Alkaline Phosphatase / blood
Biological Markers / blood,  urine
Bone Density Conservation Agents / therapeutic use*
Collagen / urine
Collagen Type I
Disease Progression
Femur Head Necrosis / complications,  diagnosis,  drug therapy*
Follow-Up Studies
Hip Fractures / etiology,  metabolism,  prevention & control*
Magnetic Resonance Imaging
Middle Aged
Peptides / urine
Prospective Studies
Treatment Outcome
Reg. No./Substance:
0/Biological Markers; 0/Bone Density Conservation Agents; 0/Collagen Type I; 0/Peptides; 0/collagen type I trimeric cross-linked peptide; 66376-36-1/Alendronate; 9007-34-5/Collagen; EC Phosphatase

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