| Does adding psychotherapy to pharmacotherapy improve social functioning in the treatment of outpatient depression? | |
| | |
MedLine Citation:
|
PMID: 17131302 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
The existence of an overall association between severity of depression and level of social functioning is well documented. To increase the probability of a long-term recovery, a normal level of social functioning is essential. It is currently unknown whether combined therapy has a better outcome than pharmacotherapy with regard to social functioning. In a 6-month randomized clinical trial in outpatients with major depression, all patients studied had a baseline score of at least 14 points on the 17-item Hamilton Depression Rating Scale (HDRS). The two conditions consist of pharmacotherapy (PhT) (N=84) and combined therapy (CoT), pharmacotherapy plus 16 sessions of short psychodynamic supportive psychotherapy (N=83). Efficacy was assessed using the 17-item HDRS, the Clinical Global Impression (CGI) Severity and Improvement scales, the Depression subscale of the Symptom Checklist-90 (SCL-90), the Quality of Life Depression Scale (QLDS), more the Groningen Social Disability Schedule (GSDS). Severity of depression decreased significantly (on the SCL-90 Depression subscale and the QLDS) more in the CoT condition. A larger improvement in social functioning was demonstrated for remitted patients than for nonremitted patients. The number of dimensions of social functioning that had improved significantly was higher in CoT than in PhT. There was a moderate advantage of the CoT condition on both depressive symptoms and level of social functioning in comparison with PhT. We also found a positive association between depression severity and level of social functioning. |
| | |
Authors:
|
Pieter J Molenaar; Jack Dekker; Rien Van; Marielle Hendriksen; Aukje Vink; Robert A Schoevers |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: Depression and anxiety Volume: 24 ISSN: 1091-4269 ISO Abbreviation: Depress Anxiety Publication Date: 2007 |
Date Detail:
|
Created Date: 2007-12-24 Completed Date: 2008-03-13 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 9708816 Medline TA: Depress Anxiety Country: United States |
Other Details:
|
Languages: eng Pagination: 553-62 Citation Subset: IM |
Affiliation:
|
Mentrum Mental Health Organization, Amsterdam, The Netherlands. pieter.molenaar@mentrum.nl |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Ambulatory Care* Antidepressive Agents / therapeutic use* Cognitive Therapy / methods* Combined Modality Therapy Depressive Disorder, Major / drug therapy, therapy* Diagnostic and Statistical Manual of Mental Disorders Female Humans Male Middle Aged Social Behavior* |
| Chemical | |
Reg. No./Substance:
|
0/Antidepressive Agents |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Factors influencing Hong Kong Chinese patients' decision-making in seeking early treatment for acute...
Next Document: Are there gender differences in catastrophic appraisals in panic disorder with agoraphobia?