Document Detail

Does Toxoplasma cause polymyositis? Report of a case of polymyositis associated with toxoplasmosis and a critical review of the literature.
MedLine Citation:
PMID:  6650138     Owner:  NLM     Status:  MEDLINE    
We report here a case of polymyositis and toxoplasmosis, and review the previous examples of this association. We suggest that in most cases this relationship is due to reactivation of latent infection in an immunocompromised host. Gross immunological aberrations underline the pathogenesis of polymyositis and these predispose the patient to the development of toxoplasmosis. Anti-protozoal therapy is necessary and produces some clinical benefit, but it does not cure the polymyositis.
W M Behan; P O Behan; I T Draper; H Williams
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Acta neuropathologica     Volume:  61     ISSN:  0001-6322     ISO Abbreviation:  Acta Neuropathol.     Publication Date:  1983  
Date Detail:
Created Date:  1984-01-27     Completed Date:  1984-01-27     Revised Date:  2007-11-09    
Medline Journal Info:
Nlm Unique ID:  0412041     Medline TA:  Acta Neuropathol     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  246-52     Citation Subset:  IM    
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MeSH Terms
Antibody Formation
HLA Antigens / analysis
Immunity, Cellular
Myositis / etiology*,  immunology
Toxoplasmosis / complications*,  immunology
Reg. No./Substance:
0/HLA Antigens

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