Document Detail

Does size really matter? Analysis of the effect of large fibroids and uterine volumes on complication rates of uterine artery embolisation.
MedLine Citation:
PMID:  20442999     Owner:  NLM     Status:  MEDLINE    
The purpose of this study was to determine whether there is a correlation between large uterine fibroid diameter, uterine volume, number of vials of embolic agent used and risk of complications from uterine artery embolisation (UAE). This was a prospective study involving 121 patients undergoing UAE embolisation for symptomatic uterine fibroids at a single institution. Patients were grouped according to diameter of largest fibroid and uterine volume. Results were also stratified according to the number of vials of embolic agent used and rate of complications. No statistical difference in complication rate was demonstrated between the two groups according to diameter of the largest fibroid (large fibroids were classified as > or = 10 cm; Fisher's exact test P = 1.00), and no statistical difference in complication rate was demonstrated according to uterine volume (large uterine volume was defined as > or = 750 cm(3); Fisher's exact test P = 0.70). 84 of the 121 patients had documentation of the number of vials used during the procedure. Patients were divided into two groups, with > or = 4 used defined as a large number of embolic agent. There was no statistical difference between these two groups and no associated increased risk of developing complications. This study showed no increased incidence of complications in women with large-diameter fibroids or uterine volumes as defined. In addition, there was no evidence of increased complications according to quantity of embolic material used. Therefore, UAE should be offered to women with large fibroids and uterine volumes.
A A Parthipun; J Taylor; I Manyonda; A M Belli
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Publication Detail:
Type:  Comparative Study; Journal Article     Date:  2010-05-05
Journal Detail:
Title:  Cardiovascular and interventional radiology     Volume:  33     ISSN:  1432-086X     ISO Abbreviation:  Cardiovasc Intervent Radiol     Publication Date:  2010 Oct 
Date Detail:
Created Date:  2010-09-07     Completed Date:  2011-01-10     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8003538     Medline TA:  Cardiovasc Intervent Radiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  955-9     Citation Subset:  IM    
Department of Radiology, St. George's Hospital, London, UK.
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MeSH Terms
Cohort Studies
Follow-Up Studies
Leiomyoma / pathology*,  therapy*,  ultrasonography
Middle Aged
Neoplasm Staging
Postoperative Complications / diagnosis,  epidemiology
Reference Values
Retrospective Studies
Risk Assessment
Treatment Outcome
Tumor Burden*
Ultrasonography, Doppler
Uterine Artery Embolization / adverse effects*,  methods
Uterine Neoplasms / pathology*,  therapy*,  ultrasonography

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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