Document Detail

Does sensitization to foods in adults occur always in the gut?
MedLine Citation:
PMID:  20664272     Owner:  NLM     Status:  MEDLINE    
It is widely accepted that, under normal conditions, the contact between allergens and the immune system via the gut results in immune tolerance. Thus, it is rather surprising that normal adults may become sensitized to foods that they have consumed a number of times without any consequence. However, the medical literature is crowded with reports suggesting that sensitization to food allergens may occur outside the intestinal tract in many instances. The present article reviews and discusses current data suggesting, either directly or indirectly, a possible initiation of food allergy in the respiratory tract or in the skin in the light of recent findings about mechanisms of tolerance and sensitization.
Riccardo Asero; Leonardo Antonicelli
Publication Detail:
Type:  Journal Article; Review     Date:  2010-07-24
Journal Detail:
Title:  International archives of allergy and immunology     Volume:  154     ISSN:  1423-0097     ISO Abbreviation:  Int. Arch. Allergy Immunol.     Publication Date:  2011  
Date Detail:
Created Date:  2010-12-14     Completed Date:  2011-01-10     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9211652     Medline TA:  Int Arch Allergy Immunol     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  6-14     Citation Subset:  IM    
Copyright Information:
Copyright © 2010 S. Karger AG, Basel.
Ambulatorio di Allergologia, Clinica San Carlo, Via Ospedale 21,Paderno Dugnano (Italy).
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MeSH Terms
Allergens / immunology
Food Hypersensitivity / immunology*
Gastrointestinal Tract / immunology*
Immune Tolerance
Plants, Edible / adverse effects,  immunology
Skin / immunology
Reg. No./Substance:

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