Document Detail

Does RNA interference influence meiotic crossing over in Drosophila melanogaster?
MedLine Citation:
PMID:  18593512     Owner:  NLM     Status:  MEDLINE    
Mutations in the RNA interference (RNAi) genes aubergine (aub), homeless and piwi were tested for effects on the frequency, distribution and coincidence of meiotic crossovers in the long arm of the X chromosome. Some increases in crossover frequency were seen in these tests, but they may have been due to a maternal effect of the balancer chromosomes that were used to maintain the RNAi mutations in stocks rather than to the RNAi mutations themselves. These same balancers produced strong zygotic interchromosomal effects when tested separately. Mutations in aub and piwi did not affect the frequency of crossing over in the centric heterochromatin of chromosome II; nor did a balancer chromosome III.
Eric W Cross; Michael J Simmons
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Genetics research     Volume:  90     ISSN:  1469-5073     ISO Abbreviation:  Genet Res (Camb)     Publication Date:  2008 Jun 
Date Detail:
Created Date:  2008-07-02     Completed Date:  2008-08-05     Revised Date:  2010-12-28    
Medline Journal Info:
Nlm Unique ID:  101550220     Medline TA:  Genet Res (Camb)     Country:  England    
Other Details:
Languages:  eng     Pagination:  253-8     Citation Subset:  IM    
Department of Genetics, Cell Biology and Development, University of Minnesota, St. Paul, MN 55108-1095, USA.
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MeSH Terms
Chromosomes / genetics
Crossing Over, Genetic*
Drosophila melanogaster / cytology*,  genetics*
RNA Interference*
X Chromosome / genetics
Reg. No./Substance:

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