| Does RNA interference influence meiotic crossing over in Drosophila melanogaster? | |
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MedLine Citation:
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PMID: 18593512 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Mutations in the RNA interference (RNAi) genes aubergine (aub), homeless and piwi were tested for effects on the frequency, distribution and coincidence of meiotic crossovers in the long arm of the X chromosome. Some increases in crossover frequency were seen in these tests, but they may have been due to a maternal effect of the balancer chromosomes that were used to maintain the RNAi mutations in stocks rather than to the RNAi mutations themselves. These same balancers produced strong zygotic interchromosomal effects when tested separately. Mutations in aub and piwi did not affect the frequency of crossing over in the centric heterochromatin of chromosome II; nor did a balancer chromosome III. |
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Authors:
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Eric W Cross; Michael J Simmons |
Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Genetics research Volume: 90 ISSN: 1469-5073 ISO Abbreviation: Genet Res (Camb) Publication Date: 2008 Jun |
Date Detail:
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Created Date: 2008-07-02 Completed Date: 2008-08-05 Revised Date: 2010-12-28 |
Medline Journal Info:
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Nlm Unique ID: 101550220 Medline TA: Genet Res (Camb) Country: England |
Other Details:
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Languages: eng Pagination: 253-8 Citation Subset: IM |
Affiliation:
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Department of Genetics, Cell Biology and Development, University of Minnesota, St. Paul, MN 55108-1095, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Animals Chromosomes / genetics Crossing Over, Genetic* Drosophila melanogaster / cytology*, genetics* Female Heterochromatin Male Meiosis* RNA Interference* X Chromosome / genetics |
| Chemical | |
Reg. No./Substance:
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0/Heterochromatin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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