Document Detail

Does primary or secondary chondrocalcinosis influence long-term survivorship of unicompartmental arthroplasty?
MedLine Citation:
PMID:  22161084     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Coexistence of degenerative arthritis and calcium pyrophosphate dihydrate (CPPD) crystals (or radiological chondrocalcinosis) with osteoarthritis (OA) of the knees is frequent at the time of arthroplasty. Several studies suggest more rapid clinical and radiographic progression with CPPD than with OA alone. However, it is unclear whether chondrocalcinosis predisposes to higher risks of progression of arthritis in other compartments.
QUESTION/PURPOSES: We questioned whether chondrocalcinosis influences clinical scores, degeneration of other compartments, rupture of the ACL, survivorship, reason for revision, or timing of failures in case of UKA.
METHODS: We retrospectively reviewed 206 patients (234 knees) who had UKAs between 1990 and 2000. Of these 234 knees, 85 had chondrocalcinosis at the time of surgery and 63 of the knees subsequently had radiographic evidence of chondrocalcinosis observed during followup. We evaluated patients with The Knee Society rating system and compared function and radiographic progression in the other compartments of patients without and with chondrocalcinosis.
RESULTS: The use of conventional NSAIDs, radiographic progression of OA in the opposite femorotibial compartment of the knee, failure of the ACL, and aseptic loosening did not occur more frequently among patients with chondrocalcinosis. The 15-year cumulative survival rates were 90% and 87% for the knees without and with chondrocalcinosis, respectively, using revision to TKA as the end point.
CONCLUSION: Our findings show chondrocalcinosis does not influence progression and therefore is not a contraindication to UKA.
Philippe Hernigou; Walter Pascale; Valerio Pascale; Yasuhiro Homma; Alexandre Poignard
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Publication Detail:
Type:  Journal Article     Date:  2011-12-13
Journal Detail:
Title:  Clinical orthopaedics and related research     Volume:  470     ISSN:  1528-1132     ISO Abbreviation:  Clin. Orthop. Relat. Res.     Publication Date:  2012 Jul 
Date Detail:
Created Date:  2012-06-07     Completed Date:  2012-08-17     Revised Date:  2013-11-06    
Medline Journal Info:
Nlm Unique ID:  0075674     Medline TA:  Clin Orthop Relat Res     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1973-9     Citation Subset:  AIM; IM    
Department of Orthopedic Surgery, University Paris East (UPEC), Hôpital Henri Mondor, 94010, Creteil, France.
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MeSH Terms
Aged, 80 and over
Arthroplasty, Replacement, Knee* / adverse effects,  instrumentation
Chi-Square Distribution
Chondrocalcinosis / complications*,  radiography
Disease Progression
Kaplan-Meier Estimate
Knee Prosthesis
Middle Aged
Osteoarthritis, Knee / complications,  radiography,  surgery*
Prosthesis Design
Prosthesis Failure
Retrospective Studies
Risk Assessment
Risk Factors
Time Factors
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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